Anthocyanidin reductase explained

Anthocyanidin reductase
Ec Number:	1.3.1.77
Cas Number:	93389-48-1

In enzymology, an anthocyanidin reductase is an enzyme that catalyzes the chemical reaction

a flavan-3-ol + 2 NAD(P)+

\rightleftharpoons an anthocyanidin + 2 NAD(P)H + H⁺

The 3 substrates of this enzyme are flavan-3-ol, NAD⁺, and NADP⁺, whereas its 4 products are anthocyanidin, NADH, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is flavan-3-ol:NAD(P)+ oxidoreductase. Other names in common use include AtANR, and MtANR. This enzyme participates in flavonoid biosynthesis.

References

• Xie DY, Sharma SB, Paiva NL, Ferreira D, Dixon RA . 2003 . Role of anthocyanidin reductase, encoded by BANYULS in plant flavonoid biosynthesis . Science . 299 . 396–399 . 12532018 . 10.1126/science.1078540 . 5605 .
• Xie DY, Sharma SB, Dixon RA . 2004 . Anthocyanidin reductases from Medicago truncatula and Arabidopsis thaliana . Arch. Biochem. Biophys. . 422 . 91–102 . 14725861 . 10.1016/j.abb.2003.12.011 . 1 .