Annette Dolphin Explained

Annette Dolphin
Birth Name:Annette Catherine Dolphin
Birth Place:Maidenhead
Thesis Title:Behavioural and Biochemical Consequences of Cerebral Noradrenaline Receptor Stimulation
Thesis Url:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.453796
Thesis Year:1977
Awards:Physiological Society Annual Review Prize Lecture (2015)

Annette Catherine Dolphin (born 1951) [1] is a Professor of Pharmacology in the Department of Neuroscience, Physiology and Pharmacology at University College London (UCL).[2] [3] [4] [5]

Education

Dolphin was educated at the University of Oxford where she was awarded a Bachelor of Arts degree in Biochemistry in 1973, and the Institute of Psychiatry at King's College London where she was awarded a PhD in 1977[6] for research on noradrenaline receptors.

Career and research

Dolphin is a leader in the field of neuronal voltage-gated calcium channels.[1] She is distinguished for her work on the regulation of calcium channel trafficking and function, and the modulation of that function by activation of G-protein coupled receptors. Her work on the control of calcium channel trafficking by auxiliary calcium channel subunits has been particularly influential. She has elucidated the topology and processing of this family of proteins.[1]

Before working at UCL, Dolphin held appointments at the Collège de France, Yale University, the National Institute for Medical Research, St George's, University of London and the Royal Free Hospital School of Medicine.

Awards and honours

Dolphin has received a number awards for her research, including the British Pharmacological Society (BPS) Sandoz Prize and the Pfizer Prize in Biology. She has also been awarded prize lectures such as the G. L. Brown Prize Lecture of The Physiological Society, the Julius Axelrod Distinguished Lecture in Neuroscience of the University of Toronto, the BPS Gary Price Memorial Lecture and, most recently, the Mary Pickford Lecture of the University of Edinburgh and the Physiological Society Annual Review Prize Lecture in 2015.[7]

She was elected a Fellow of the Academy of Medical Sciences (FMedSci) in 1999[8] and a Fellow of the Royal Society (FRS) in 2015.[7]

Notes and References

  1. Web site: Anon. 2015. Professor Annette Dolphin FMedSci FRS . The Royal Society . 2015-05-12 . https://web.archive.org/web/20150512101654/https://royalsociety.org/people/fellowship/2015/annette-dolphin/ . London.
  2. Dolphin. Annette C.. Subunits of Voltage-Gated Calcium Channels. Journal of Bioenergetics and Biomembranes. 35. 6. 2003. 599–620. 0145-479X. 10.1023/B:JOBB.0000008026.37790.5a. 15000522. 1425656.
  3. 17088553. 1859964. 2006. Field. M. J.. Identification of the alpha2-delta-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin. Proceedings of the National Academy of Sciences. 103. 46. 17537–42. Cox. P. J.. Stott. E. Melrose. H. Offord. J. Su. T. Z.. Bramwell. S. Corradini. L. England. S. Winks. J. Kinloch. R. A.. Hendrich. J. Dolphin. A. C.. Webb. T. Williams. D. 10.1073/pnas.0409066103. 2006PNAS..10317537F. free.
  4. 9481669. 2230712. 1998. Dolphin. A. C.. Mechanisms of modulation of voltage-dependent calcium channels by G proteins. The Journal of Physiology. 506. 3–11 . 1 . 10.1111/j.1469-7793.1998.003bx.x.
  5. Dolphin. A. C.. Errington. M. L.. Bliss. T. V. P.. Long-term potentiation of the perforant path in vivo is associated with increased glutamate release. Nature. 297. 5866. 1982. 496–497. 0028-0836. 10.1038/297496a0. 6123949. 1982Natur.297..496D. 4255128.
  6. PhD. King's College London . Behavioural and Biochemical Consequences of Cerebral Noradrenaline Receptor Stimulation. Annette Catherine. Dolphin. 1977. 729771638.
  7. Web site: https://web.archive.org/web/20151117101103/https://royalsociety.org/people/annette-dolphin-11346/ . 2015-11-17 . Professor Annette Dolphin FMedSci FRS. . London . Anon. 2015 . One or more of the preceding sentences incorporates text from the royalsociety.org website where:
  8. Web site: Professor Annette Dolphin FRS FMedSci. London. Academy of Medical Sciences. 7 June 2015. 22 December 2015. https://web.archive.org/web/20151222173559/http://www.acmedsci.ac.uk/fellows/fellows-directory/ordinary-fellows/professor-annette-dolphin/. dead.

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