Anne Monique Nuyt Explained

Anne Monique Nuyt
Workplaces:Université de Montréal
Collège de France
Iowa State University
McGill University
Alma Mater:Université de Sherbrooke

Anne Monique Nuyt is a Canadian paediatrician who is Professor of Neonatology and Canada Research Chair in Prematurity and Developmental Origins of Cardiovascular Health and Diseases at the Université de Montréal. Her research considers how perinatal oxidative stress can alter the structural development and function of the cardiovascular system.

Early life and education

Nuyt trained in medicine at the Université de Sherbrooke.[1] After earning her medical degree, she completed her residency in Sherbrooke, before moving to McGill University for a fellowship in perinatal and neonatal medicine.[1] In 1993, Nuyt joined Iowa State University, where she focused on perinatal cardiovascular physiology. She continued investigating cardiovascular science, supported by the Canadian Institutes of Health Research, at the Collège de France.[1]

Research and career

Nuyt investigates how oxidative stress after birth impacts the structural development and function of cardiovascular systems.[2] [3] [4] Alongside other ante- and neo-natal factors, these stresses can alter the onset of hypertension in adulthood. Her laboratory performs investigations by studying animal models. She has shown that it is possible to modify a rat's diet and trigger delayed growth in their offspring as well as hypertension in adulthood. Similarly, she has shown that if rats are exposed to high oxygen concentrations in the first days of their lives they experience vascular dysfunction and hypertension. Nuyt is interested in how the mechanisms that underpin the development of hypertension. To evaluate other factors, Nuyt performs clinical trials in mother-child cohorts. She is particularly interested in the development of screening strategies and targeted therapies.[5]

Nuyt has demonstrated that babies born very prematurely (extreme preemies) are considerably more likely to suffer from high blood pressure as adults.[6] She also showed that women who are born prematurely are more like to have their own babies prematurely.[7] [8]

During the COVID-19 pandemic, Canada experienced a surge in the number of young people with eating disorders and suicidal thoughts. Nuyt called for the prioritisation of adolescent mental health to limit the long-term consequences of the pandemic on young people.[9] She was elected to the Canadian Academy of Health Sciences in 2021.[5]

Awards and honours

Notes and References

  1. Web site: Government of Canada. Canadian Institutes of Health Research. 2003-05-22. IHDCYH Institute Advisory Board Members – Biographies - CIHR. 2022-01-13. cihr-irsc.gc.ca.
  2. Web site: Biography, Anne Monique Nuyt, M.D.. live. CHUSJ - Centre de Recherche. https://web.archive.org/web/20210520124354/https://www.chusj.org/Bio?id=0a2f771b-2ba5-478f-afea-b09df65cf503&lang=en . 2021-05-20 .
  3. Web site: Anne-Monique Nuyt - Département de pédiatrie - Université de Montréal. 2022-01-13. Département de pédiatrie. fr-FR.
  4. Web site: Quebec Research Network in Perinatal Determinants of Children Health (Perinatal Research Network) - Fonds de recherche du Québec - FRQ. 2022-01-13. Fonds de recherche du Québec. en-US.
  5. Web site: 2021-08-31. article. 2022-01-13. nouvelles.umontreal.ca. en.
  6. Web site: Reinberg. Steven. Reporter. Healthday. Extreme preemies may be at risk for high blood pressure as adults. 2022-01-13. medicalxpress.com. en.
  7. Web site: Women Born Early at Greater Risk of Delivering Preemies, Study Suggests. 2022-01-13. WebMD. en.
  8. Web site: Preemie female babies risk difficult pregnancies later on: study. 2022-01-13. torontosun. en-CA.
  9. Web site: Quebec must prioritize mental health of adolescents, pediatricians say. 2022-01-13. montrealgazette. en-CA.
  10. Yzydorczyk. Catherine. Comte. Blandine. Huyard. Fanny. Cloutier. Anik. Germain. Nathalie. Bertagnolli. Mariane. Nuyt. Anne Monique. January 2013. Developmental programming of eNOS uncoupling and enhanced vascular oxidative stress in adult rats after transient neonatal oxygen exposure. Journal of Cardiovascular Pharmacology. 61. 1. 8–16. 10.1097/FJC.0b013e318274d1c4. 1533-4023. 23011469.
  11. Pladys. P.. Sennlaub. F.. Brault. S.. Checchin. D.. Lahaie. I.. Lê. N. L. O.. Bibeau. K.. Cambonie. G.. Abran. D.. Brochu. M.. Thibault. G.. 2005-12-01. Microvascular rarefaction and decreased angiogenesis in rats with fetal programming of hypertension associated with exposure to a low-protein diet in utero. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 289. 6. R1580–R1588. 10.1152/ajpregu.00031.2005. 0363-6119.
  12. Web site: 2016 Certificates of Excellence. live. 2022-01-13. https://web.archive.org/web/20220113222232/https://hypertension.ca/wp-content/uploads/2017/11/2016_CertificatesofExcellence-EN.pdf . 2022-01-13 .
  13. Web site: Government of Canada. Industry Canada. 2012-11-29. Canada Research Chairs. 2022-01-13. www.chairs-chaires.gc.ca.