| Anne-Marie Escoffier | |
| Office: | Minister Delegate to Decentralization |
| President: | François Hollande |
| Primeminister: | Jean-Marc Ayrault |
| Successor: | André Vallini |
| Term Start: | 21 June 2012 |
| Term End: | 31 March 2014 |
| Office2: | Member of the French Senate for Aveyron |
| Term Start2: | 2008 |
| Term End2: | 2014 |
| Predecessor2: | Jean Puech |
| Successor2: | Jean-Claude Luche |
| Birth Date: | 15 August 1942 |
| Birth Place: | Dax, France |
| Nationality: | French |
| Party: | Radical Party of the Left |
| Alma Mater: | Jean Moulin University Lyon 3 |
Anne-Marie Escoffier (born 15 August 1942 in Dax, Landes) is a French politician and a former member of the Senate of France. She represented the Aveyron department as a member of the Radical Party of the Left.