Anna-Lise Williamson Explained

Anna-Lise Williamson
Fields:	Virology
Education:	University of the Witwatersrand Doctor of Philosophy (PhD), Virology
Thesis Title:	An Electron Microscope and Immunocytochemical Study of Jaagsiekte
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Thesis Year:	1985
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Anna-Lise Williamson MASSAf is a Professor of Virology at the University of Cape Town. Williamson obtained her PhD from the University of the Witwatersrand in 1985. Her area of expertise is human papillomavirus, but is also known on an international level for her work in developing vaccines for HIV. These vaccines have been introduce in phase 1 of clinical trial. Williamson has published more than 120 papers.

Education

Williamson received a PhD at the University of the Witwatersrand in 1985. Her Ph.D. thesis was entitled "An Electron Microscopic and Immunocytochemical Study of Jaagsiekte". Williamson was also a fellow at the Royal Society of South Africa and at the University of Cape Town.

Accomplishments

Anna-Lise Williamson is the Director of University of the Cape Town vaccine Research group GLP. Her area of expertise and what she is best known for is Human Papillomavirus and HIV Vaccines.

Awarded a Chair in Vaccinology 2008 (South African Research Chairs Initiative)
Head of World Health Organization human papillomavirus Labnet lab for the Africa Region
Joint Head of University of Cape Town, National Institute for communicable Diseases, and National health Laboratory Service Molecular Epidemiology Laboratory
Member of the South African HPV Advisory Board

Contributions

Anna-Lise Williamson is the head of the HIV vaccine development and human papilloma research group at the University of Cape Town. There, Williamson and a team of over 30 people are developing vaccines for HIV-1 subtype C virus. This strain is known to be the most Virulent, and known to be the principle strain that leads to AIDS.The goal of the investigation is to create affordable and effective HIV-1 C vaccines, that would increase the longevity of memory T cells and develop a more functional use of the CD4+ and CD8+ cell response. Two vaccines have been selected to move forward in clinical trials. These vaccines are DNA vaccines and a modified vaccinia virus Ankara vaccine. The vaccines were developed as part of the South African AIDS Vaccine Initiative (SAAVI).

Selected publications

Anna-Lise Williamson has published over 120 papers. Her publications mainly consists of her area of expertise addressing HIV vaccine development, HIV virus, and HPV virus.

Marais . D. J. . Constant . D. . Allan . B. . Carrara . H. . Hoffman . M. . Shapiro . S. . Morroni . C. . Williamson . A.-L. . Cervical Human Papillomavirus (HPV) Infection and HPV Type 16 Antibodies in South African Women . Journal of Clinical Microbiology . 46 . 2 . 2007 . 732–739 . 0095-1137 . 10.1128/JCM.01322-07. 2238115 . 18077644. The purpose of this publication is to identify subtypes of HIV-1 in both homosexual and heterosexual males in the Cape Town, South Africa population.
Shephard . Enid . Burgers . Wendy A. . Van Harmelen . Joanne H. . Monroe . James E. . Greenhalgh . Trish . Williamson . Carolyn . Williamson . Anna-Lise . A Multigene HIV Type 1 Subtype C Modified Vaccinia Ankara (MVA) Vaccine Efficiently Boosts Immune Responses to a DNA Vaccine in Mice . AIDS Research and Human Retroviruses . 24 . 2 . 2008 . 207–217 . 0889-2229 . 10.1089/aid.2007.0206. 18240963 . The goal of this publication is to identify the prevalence and risk factors associated with HPV Infection, and HPV-16 antibody in the population of Southern Africa.
Adler . D. . Bruyn . G. d. . Laher . F. . Gray . G. . Allan . B. R. . Williamson . A.-L. . Human Papillomavirus Genotype Distribution among Human Immunodeficiency Virus (HIV)-Infected and Non-HIV-Infected Women in Soweto, South Africa . Journal of Clinical Microbiology . 46 . 12 . 2008 . 4109–4110 . 0095-1137 . 10.1128/JCM.01667-08 . 18945842 . 2593278.
Burgers . W. A. . Chege . G. K. . Muller . T. L. . van Harmelen . J. H. . Khoury . G. . Shephard . E. G. . Gray . C. M. . Williamson . C. . Williamson . A.-L. . Broad, high-magnitude and multifunctional CD4+ and CD8+ T-cell responses elicited by a DNA and modified vaccinia Ankara vaccine containing human immunodeficiency virus type 1 subtype C genes in baboons . Journal of General Virology . 90 . 2 . 2009 . 468–480 . 0022-1317 . 10.1099/vir.0.004614-0. 19141458 . free .
Marais . Dianne J. . Carrara . Henri . Ramjee . Gita . Kay . Patti . Williamson . Anna-Lise . HIV-1 seroconversion promotes rapid changes in cervical human papillomavirus (HPV) prevalence and HPV-16 antibodies in female sex workers . Journal of Medical Virology . 81 . 2 . 2009 . 203–210 . 0146-6615 . 10.1002/jmv.21343. 19107974 . 32432184 .

References

Sources

Mckune . Craig . SA vaccine trials launched, but future funding not secure . South African Journal of Science . July/August 2009 . 243–244 . 13 May 2015 . https://web.archive.org/web/20150518084835/http://www.sajs.co.za/sites/default/files/publications/pdf/22-78-1-PB.pdf . 18 May 2015 . dead .
Ph.D. . Anna-lise . Payne . An Electron Microscopic And Immunocytochemical Study Of Jaagsiekte . University of The Witwatersrand . 1984 .