| Official Name: | Ankofabe |
| Pushpin Map: | Madagascar |
| Pushpin Label Position: | bottom |
| Pushpin Map Caption: | Location in Madagascar |
| Pushpin Mapsize: | 180 |
| Subdivision Type: | Country |
| Subdivision Type1: | Region |
| Subdivision Name1: | Analanjirofo |
| Subdivision Type2: | District |
| Subdivision Name2: | Maroantsetra |
| Population As Of: | 2018 |
| Population Total: | 10,561 |
| Population Blank1 Title: | Ethnicities |
| Population Blank2 Title: | Religions |
| Timezone: | EAT |
| Utc Offset: | 3 |
| Coordinates: | -15.5°N 86°W |
| Elevation M: | 10 |
Ankofabe is a town and commune (Malagasy: kaominina) in Madagascar. It belongs to the district of Maroantsetra, which is a part of Analanjirofo Region. The population of the commune was estimated to be approximately 10,561 in 2018.
Primary and junior level secondary education are available in town. The majority 95% of the population of the commune are farmers. The most important crops are rice and vanilla, while other important agricultural products are coffee and cloves. Services provide employment for 5% of the population.