| Anita Carol Klein Hopper | |
| Workplaces: | Ohio State University Pennsylvania State University University of Massachusetts Medical School |
| Alma Mater: | University of Illinois at Chicago University of Illinois Urbana-Champaign |
| Thesis Title: | An investigation into the replication of satellite tobacco necrosis virus and tobacco necrosis virus RNA genomes. |
| Thesis Url: | http://www.worldcat.org/oclc/77219389 |
| Thesis Year: | 1972 |
Anita Hopper is an American molecular geneticist who is a professor at the Ohio State University. She studies the mechanisms of distribution of RNA between the nucleus and cytoplasm. She is a Fellow of the American Academy of Microbiology and the American Association for the Advancement of Science and was elected a Member of the National Academy of Sciences in 2021.
Hopper was an undergraduate student at the University of Illinois at Chicago, where she studied biology. She moved to the University of Illinois Urbana-Champaign for her graduate studies, where she specialized in cell biology. Hopper studied the replication of satellite tobacco necrosis virus.[1] After completing her doctoral research she moved to the University of Washington, where she spent four years as a postdoctoral research associate.
Hopper joined the faculty at the University of Massachusetts Medical School, and was promoted to associate professor. She was appointed professor at the Pennsylvania State University in 1979, where she spent almost thirty years before joining the Ohio State University as chair of the Department of Molecular Genetics.[2]
Hopper makes use of Saccharomyces cerevisiae (yeast) as a model system to study processing and intracellular trafficking of tRNAs.[3] Almost all RNAs involved in protein synthesis are generated in the nucleus but function in the cytoplasm (and vice versa). Hopper both processes occur along nuclear export pathways, where export quality is controlled by the translation machinery itself. She showed that tRNAs from the cytoplasm accumulate in the nucleus under particular stress conditions.
Hopper's area expertise include:[4] intracellular trafficking of RNA and proteins, RNA processing and yeast genetics and genomics.
Hopper was married to biochemist James Hopper, with whom she had one daughter.[12]