Anita Corbett | |
Birth Name: | Anita Hargrave Corbett |
Workplaces: | Emory University |
Alma Mater: | Colgate University (BS) Vanderbilt University (PhD) |
Fields: | mRNA processing Polyadenylation Gene expression Intellectual disability |
Thesis Title: | Regulation of the catalytic cycle of topoisomerase II |
Thesis Url: | https://worldcat.org/en/title/30332920 |
Thesis Year: | 1992 |
Anita Hargrave Corbett is an American biochemist who is the Samuel C. Dobbs Professor in the Department of Biology at Emory University. Her research investigates the molecular basis for disease, the regulation of protein import and mRNA export. She is a Fellow of the American Association for the Advancement of Science and the American Society for Biochemistry and Molecular Biology.
As a high school student, Corbett took part in the National Science Bowl. She has said that her high school chemistry teacher made her believe she could be a chemist, and encouraged her to take AP Chemistry. She was an undergraduate student at Colgate University,[1] where she became interested in biochemistry, and studied the activation and inhibition of bovine carbonic anhydrase.[2] Corbett was a doctoral researcher at Vanderbilt University,[3] where she studied the regulation of topoisomerase II supervised by .[4]
After her PhD, she moved to Harvard Medical School as a postdoctoral researcher with Pamela Silver.[5]
In 2003, Corbett was the first woman to be tenured in the Emory University School of Medicine. Her research investigates the regulation of biological processes, including the import of proteins and export of mRNA. She studies these processes using model systems of yeast, Drosophila and laboratory mice.[6] [7] It is well understood that disease is linked to mutations in genes encoding structural RNA exosome subunits. Corbett linked mutations in one particular subunit, EXOSC5, to poor clinical outcomes.[8] She has extensively investigated RNA-binding proteins, which are involved with various stages of gene expression.[9]