Illicium verum explained

Illicium verum (star anise or badian, Chinese star anise, star anise seed, star aniseed and star of anise) is a medium-sized evergreen tree native to northeast Vietnam and South China. It is a spice that closely resembles anise in flavor and is obtained from the star-shaped pericarps of the fruit of I. verum which are harvested just before ripening. Star anise oil is a highly fragrant oil used in cooking, perfumery, soaps, toothpastes, mouthwashes, and skin creams. Until 2012, when they switched to using genetically modified E. coli, Roche Pharmaceuticals used up to 90% of the world's annual star anise crop to produce oseltamivir (Tamiflu) via shikimic acid.[1]

Etymology and nomenclature

Star anise
C:八角
P:bājiǎo
L:"eight-horns"
Y:baat-gok
Poj:peh-kak

Illicium comes from the Latin meaning "entice" or "seduce".[2]

Verum means "true" or "genuine".

The name "badian" appears to derive, via French, from the apparently descriptive Chinese name for it,,, lit. "eight horns". However, a derivation from the Persian Persian: [[wikt:بادیان|بادیان]] , "fennel", exists, with the Oxford English Dictionary indicating that its origin before that is unknown.[3]

Description

Leaves are aromatic, simple and lanceolate, obovate-elliptic or elliptic, size of 5–15 cm × 2–5 cm, coriaceous to thickly coriaceous.[4] The leaves are 5–15 cm × 1.5–5 cm, apex acute, lower side pubescent.[4] Flowers are solitary, bisexual, pink to dark red, axillary or subterminal.[4] The perianth has lobes 7–12, arranged spirally; stamens number of 11–20, arranged spirally, with short, thick filaments; carpels usually 8, free, arranged in a single whorl. Flower peduncle size is 1.5–4 cm, tepals number range from seven to twelve, and are broadly elliptic to broadly ovate, anthers size is 1–1.5 mm, pollen grains trisyncolpate.

The fruit is a capsule-like follicetum, star-shaped, reddish-brown, consisting of six to eight follicles arranged in a whorl.[4] Each follicle is boat-shaped, 1–2 cm long, rough and rigid, color reddish-brown, with 1 seed, opening along the ventral edge when ripe.[4] carpels size of 10 mm long, boat-shaped; they are hard and wrinkled, containing one seed. Seeds are brown, compressed ovoid, smooth, shiny and brittle with approximate size of 8–9 mm × 6 mm.[4] [5]

Differences with similar taxa:Illicium anisatum had smaller fruits that does not form a regular star due to the abortion of some carpels. Also fruit follicles are not swollen in the middle and had a more pointed apex. Also usually had more than 8 follicles and the fruit has weaker odour. The seeds in Illicium anisatum are flat or almost spherical.[4] [5]

Use

Culinary use

Star anise contains anethole, the same compound that gives anise, an unrelated plant, its flavor. Star anise has come into use in the West as a less expensive substitute for anise in baking, as well as in liquor production, most distinctively in the production of the liqueur Galliano.[6] Star anise enhances the flavor of meat.[7]

It is used as a spice in preparation of biryani and masala chai all over the Indian subcontinent. It is widely used in Chinese cuisine, and in Malay and Indonesian cuisines. It is widely grown for commercial use in China, India, and most other countries in Asia. Star anise is an ingredient of the traditional five-spice powder of Chinese cooking. It is also a major ingredient in the making of phở, a Vietnamese noodle soup.

It is also used in the French recipe of mulled wine, vin chaud (hot wine). If allowed to steep in coffee, it deepens and enriches the flavor. The pods can be used in this manner multiple times by the potful or cup, as the ease of extraction of the taste components increases with the permeation of hot water.

Drug precursor

See main article: Oseltamivir total synthesis.

Star anise is the major source of the chemical compound shikimic acid, a primary precursor in the pharmaceutical synthesis of the antiinfluenza drug oseltamivir (Tamiflu).[8] [9] [10] An industrial method for the production of shikimic acid using fermentation of E. coli bacteria was discovered in 2005,[11] [12] and applied in the 2009 swine flu pandemic to address Tamiflu shortages, eventually reversing price increases for star anise as a raw material of shikimic acid.[13] As of 2018, fermentation of E. coli was the manufacturing process of choice to produce shikimic acid for synthesis of Tamiflu.[8] [9]

Toxicity of related species

Illicium verum is not toxic. However, other related species are toxic.

Japanese star anise (Illicium anisatum), a similar tree, is highly toxic and inedible; in Japan, it has instead been burned as incense. Cases of illness, including "serious neurological effects, such as seizures", reported after using star anise tea may be a result of deliberate economically motivated adulteration with this species. Japanese star anise contains the neurotoxin anisatin,[14] which also causes severe inflammation of the kidneys (nephritis), urinary tract, and digestive organs when ingested.[15]

Swamp star anise Illicium parviflorum, a similar tree found in the southern United States, is highly toxic and should not be used for folk remedies or as a cooking ingredient.[16]

ISO Standardization

Identification

Differentiation from other species

Joshi et al. have used fluorescent microscopy and gas chromatography[18] to distinguish the species, while Lederer et al. employed thin layer chromatography with HPLC-MS/MS.[19]

Specifications

Notes and References

  1. News: Schönholzer . Fabio . Dried Stars . UZH News . . en . . 15 March 2018 . 21 February 2021.
  2. Gledhill, David (2008). "The Names of Plants". Cambridge University Press. (hardback), (paperback). pp 210, 400
  3. "badian, n.". OED Online. September 2019. Oxford University Press. https://www-oed-com.library.access.arlingtonva.us/view/Entry/14568?redirectedFrom=badiane (accessed 8 September 2019).
  4. Web site: Illicium verum . PlantUse . 8 November 2020.
  5. Wang . Guo-Wei . Hu . Wen-Ting . Huang . Bao-Kang . Lu-Ping . Qin . Illicium verum: A review on its botany, traditional use, chemistry and pharmacology . Journal of Ethnopharmacology . 2011 . 136 . 1 . 10–20 . 10.1016/j.jep.2011.04.051. 21549817 .
  6. Web site: Galliano. 13 March 2016.
  7. Spaghetti Bolognese . In Search of Perfection . Heston Blumenthal. BBC Two.
  8. Bilal . Muhammad . Wang . Songwei . Iqbal . Hafiz M. N. . Zhao . Yuping . Hu . Hongbo . Wang . Wei . Zhang . Xuehong . Metabolic engineering strategies for enhanced shikimate biosynthesis: current scenario and future developments . Applied Microbiology and Biotechnology. 102 . 18 . 16 July 2018 . 0175-7598 . 30014168 . 10.1007/s00253-018-9222-z . 7759–7773. 49870582 .
  9. Web site: Oseltamivir (Tamiflu): Uses, Dosage, Side Effects . Drugs.com . 8 May 2018 . 31 January 2019.
  10. Wang . G. W. . Hu . W. T. . Huang . B. K. . Qin . L. P. . Illicium verum: A review on its botany, traditional use, chemistry and pharmacology . 10.1016/j.jep.2011.04.051 . Journal of Ethnopharmacology . 136 . 1 . 10–20 . 2011 . 21549817.
  11. D. . Bradley . Star role for bacteria in controlling flu pandemic?. Nature Reviews Drug Discovery . 4. 12. 945–946. Dec 2005 . 1474-1776. 16370070. 10.1038/nrd1917. 30035056 .
  12. Kremer . M.. Bongaerts. Bovenberg . J. . R. . S.. Orf. Wubbolts. Krämer . U. . S. . M. . L.. Metabolic engineering for microbial production of shikimic acid. Metabolic Engineering. 5. Raeven. Müller. 4. 277–283. 2003. 14642355. 10.1016/j.ymben.2003.09.001.
  13. Web site: Louisa Lim . Swine flu bumps up price of Chinese spice . US National Public Radio . 18 May 2009.
  14. Web site: Anisatin . PubChem, National Library of Medicine, US National Institutes of Health . 11 May 2019. 17 May 2019.
  15. Perret . C. . Tabin . R. . Marcoz . J.-P. . Llor . J. . Cheseaux . J.-J. . Malaise du nourrisson pensez à une intoxication à l'anis étoilé . Apparent life-threatening event in infants: think about star anise intoxication. 10.1016/j.arcped.2011.03.024 . Archives de Pédiatrie . 18 . 7 . 750–753 . 2011 . 21652187 .
  16. Web site: How to grow star anise. 2015-10-28.
  17. Web site: International Organization for Standardization . International Organization for Standardization . ISO 676:1995 Spices and condiments – Botanical nomenclature . 8 June 2009 .
  18. Joshi . Vaishali C. . Ragone . S . Bruck . IS . Bernstein . JN . Duchowny . M . Peña . BM. Rapid and easy identification of Illicium verum Hook. f. and its adulterant Illicium anisatum Linn. by fluorescent microscopy and gas chromatography . Journal of AOAC International . 88 . 3 . 703–706 . 2005 . 10.1093/jaoac/88.3.703 . 10 November 2007 . 16001842 . free .
  19. Lederer . Ines . Schulzki . G . Gross . J . Steffen . JP . Combination of TLC and HPLC-MS/MS methods. Approach to a rational quality control of Chinese star anise . Journal of Agricultural and Food Chemistry . 54 . 6 . 1970–1974 . 2006 . 16536563 . 10.1021/jf058156b.
  20. Web site: International Organization for Standardization . International Organization for Standardization . ISO 11178:1995 Star anise (Illicium verum Hook. f.) – Specification . 8 June 2009 .