| Andrew McKenzie | |
| Birth Name: | Andrew Neil James McKenzie |
| Fields: | Immunology Autoimmunity Molecular biology |
| Workplaces: | Laboratory of Molecular Biology University of Cambridge National Institute for Medical Research[1] |
| Education: | University of London (PhD) |
| Thesis Title: | Cellular and humoral aspects of the immune response of the larval stages of Calliphora vomitoria L. (Insecta: Diptera) |
| Thesis Url: | http://catalogue.libraries.london.ac.uk/record=b1581536 |
| Thesis Year: | 1988 |
| Doctoral Advisors: | )--> |
Andrew Neil James McKenzie is a molecular biologist and group leader in the Medical Research Council (MRC) Laboratory of Molecular Biology (LMB).
McKenzie was educated at the University of London where he was awarded a PhD for research on the immune response of the bluebottle fly (Calliphora vomitoria),[2] covering both humoral immunity and cell-mediated immunity.
McKenzie's research investigates how the innate immune system and adaptive immune system protect the body from infection, but can also lead to inflammation and pathology. He has defined and characterised how biological networks orchestrate responses to pathogens and how dysregulation of these biological pathways can lead to diseases such as asthma and allergy.[3]
His identification of the cytokine Interleukin 13 and the subsequent unearthing of its central role in allergic asthma led to his discovery of type-2 innate lymphoid cells (ILC2).[4] [5] These cells secrete large quantities of cytokines and represent a new druggable biological target for intervention in inflammation and infection.
McKenzie was elected a Fellow of the Royal Society (FRS) in 2017[6] and a Fellow of the Academy of Medical Sciences (FMedSci) in 2011.[7]