Andreas Hierlemann Explained

Andreas Hierlemann
Nationality:German
Field:Biosystems engineering
Work Institutions:ETH Zurich
Known For:Development of CMOS chemical and biomicrosensors, CMOS high-density microelectrode arrays

Andreas Hierlemann (17 August 1964) is a German chemist and professor of Biosystems Engineering at ETH Zurich. He is known for his work in the field of CMOS-based chemical and biomicrosensors and high-density microelectrode arrays.

Life

From 1985 to 1991, Hierlemann studied chemistry at the University of Tübingen, Germany. He received a PhD from the University of Tübingen in 1996 for his work on Mass-sensitive detection of organic volatiles using modified polysiloxanes. 1997–98 he held postdoctoral positions at Texas A&M University in College Station, Texas, USA, and at Sandia National Laboratories in Albuquerque, New Mexico, USA. From 1999 to 2004 he was research team leader at the Physical Electronics Laboratory in the Department of Physics of ETH Zürich, Switzerland, becoming associate professor for microsensors in 2004. In 2008 he was named full professor of Biosystems Engineering, Department of Biosystems Science and Engineering of ETH Zurich in Basel, Switzerland.

Scientific contribution

Hierlemann's research initially was mostly in the area of chemical sensors and microsensors.[1] [2] In particular, he worked on the detection of organic volatiles and the discrimination of enantiomers in the gas phase.[3] [4] He then adopted microtechnology and, specifically, CMOS-based microelectronics to devise complex microsensor systems.[5] [6] The current interdisciplinary research is rooted in engineering and physics and targeted at questions in biology and medicine. It includes the development of CMOS-based integrated chemical and biomicrosystems, as well as bioelectronics and high-density microelectrode arrays.[7] [8] [9] The high-density microelectrode arrays are used for fundamental research in information processing and signaling characteristics of neurons or brain cells. Moreover, the research group is engaged in the development of microfluidics for investigating the characteristics of single cells and microtissues.

Applications of Hierlemann's and his group's technologies are in the fields of systems biology, drug testing, personalized medicine, and neuroscience.

Awards

Publication list

External links

Notes and References

  1. Hagleitner . C. . Hierlemann . A. . Lange . D. . Kummer . A. . Kerness . N. . Brand . O. . Baltes . H. . Smart single-chip gas sensor microsystem . Nature . Springer Science and Business Media LLC . 414 . 6861 . 2001 . 0028-0836 . 10.1038/35104535 . 293–296. 11713525 . 2001Natur.414..293H . 4348126 .
  2. Hierlemann . Andreas . Gutierrez-Osuna . Ricardo . Higher-Order Chemical Sensing . Chemical Reviews . American Chemical Society (ACS) . 108 . 2 . 17 January 2008 . 0009-2665 . 10.1021/cr068116m . 563–613. 18198903 .
  3. Bodenhöfer . K. . Hierlemann . A. . Seemann . J. . Gauglitz . G. . Koppenhoefer . B. . Gpel . W. . Chiral discrimination using piezoelectric and optical gas sensors . Nature . Springer Science and Business Media LLC . 387 . 6633 . 1997 . 0028-0836 . 10.1038/42426 . 577–580. 9177343 . 1997Natur.387..577B . 4364747 .
  4. Kurzawski . Petra . Bogdanski . Anja . Schurig . Volker . Wimmer . Reinhard . Hierlemann . Andreas . Opposite Signs of Capacitive Microsensor Signals upon Exposure to the Enantiomers of Methyl Propionate Compounds . Angewandte Chemie International Edition . Wiley . 47 . 5 . 18 January 2008 . 1433-7851 . 10.1002/anie.200704346 . 913–916. 18098249 .
  5. Book: Hierlemann, A . Integrated chemical microsensor systems in CMOS technology . Springer . Berlin New York . 2005 . 978-3-540-27372-1 . 262677851 .
  6. Hafizovic . S. . Barrettino . D. . Volden . T. . Sedivy . J. . Kirstein . K.-U. . Brand . O. . Hierlemann . A. . Single-chip mechatronic microsystem for surface imaging and force response studies . Proceedings of the National Academy of Sciences . 101 . 49 . 29 November 2004 . 0027-8424 . 10.1073/pnas.0405725101 . 17011–17015. 15569945 . 535376 . 2004PNAS..10117011H . free .
  7. Frey . U. . Egert . U. . Heer . F. . Hafizovic . S. . Hierlemann . A. . Microelectronic system for high-resolution mapping of extracellular electric fields applied to brain slices . Biosensors and Bioelectronics . Elsevier BV . 24 . 7 . 2009 . 0956-5663 . 10.1016/j.bios.2008.11.028 . 2191–2198. 19157842 .
  8. Hierlemann . A . Frey . U . Hafizovic . S . Heer . F . Growing Cells Atop Microelectronic Chips: Interfacing Electrogenic Cells In Vitro With CMOS-Based Microelectrode Arrays . Proceedings of the IEEE . Institute of Electrical and Electronics Engineers (IEEE) . 99 . 2 . 2011 . 0018-9219 . 10.1109/jproc.2010.2066532 . 252–284. 2578216 .
  9. Bakkum . Douglas J. . Frey . Urs . Radivojevic . Milos . Russell . Thomas L. . Müller . Jan . Fiscella . Michele . Takahashi . Hirokazu . Hierlemann . Andreas . Tracking axonal action potential propagation on a high-density microelectrode array across hundreds of sites . Nature Communications . Springer Science and Business Media LLC . 4 . 1 . 19 July 2013 . 2041-1723 . 10.1038/ncomms3181 . 2181. 23867868 . 5419423 . 2013NatCo...4.2181B .
  10. Web site: Current IEEE Corporate Award Recipients.
  11. http://www.eurosensors.net//index.php?option=com_content&task=view&id=39&Itemid=78 Eurosensors Fellow 2008
  12. Web site: DECHEMA | DECHEMA Prize-winners . December 6, 2013 . https://web.archive.org/web/20131206230349/http://www.dechema.de/index.php?id=1030&nonactive=1&lang=en . 6 December 2013 . dead.

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