Romano Bobone (died 1189, Rome) was an Italian cardinal.
His year and place of birth are unknown, but this is presumed to be Rome, where his family was already well-represented in the Roman Curia. He and cardinal Soffredo were made papal legates to Philip II of France and Henry II of England, negotiating a two-year truce between them. On 21 March 1188, pope Clement III made him cardinal deacon of San Giorgio in Velabro. According to Aubery, he moved to a church in Porto.