| Andradina Biological Reserve | |
| Alt Name: | Reserva Biológica de Andradina |
| Iucn Category: | Ia |
| Map: | Brazil |
| Relief: | yes |
| Coordinates: | -20.8807°N -51.3353°W |
| Designation: | Biological reserve |
| Created: | 17 December 1985 |
| Administrator: | Agencia Paulista de Tecnologia das Agronegócios |
Andradina Biological Reserve (Portuguese: Reserva Biológica de Andradina) is a biological reserve administered by São Paulo state, Brazil.
The reserve was created by São Paulo state on 17 December 1985 as a biological reserve under the terms of the Federal Law 4.771 of 15 September 1965. It had formerly been the Estação Experimental de Zootecnia de Andradina.It is located in the municipality of Andradina.It covers an area of
The reserve is home to endangered titi monkeys.Threats include encroachment of people, cattle and horses, accidental fires, poaching and siltation and pollution of the water courses.