Anatole Klyosov Explained

Anatole A. Klyosov (Russian: Анато́лий Алексе́евич Клёсов; born 20 November 1946 in Chernyakhovsk) is a Russian scientist who worked in the fields of physical chemistry, enzyme catalysis, and industrial biochemistry. In 1989 Klyosov immigrated to the US. He spent most of his career developing ways to use enzymes to convert agricultural waste products into useful products — first to convert cotton waste to glucose in the USSR, and later in the US, turning paper mill waste into useful products. He later helped found a company, and later joined it as CSO, that was founded to use enzymes to alter existing anticancer drugs via glycosylation.

Career

Klyosov earned Ph.D. and D.Sc. degrees in physical chemistry, and an M.S. degree in enzyme kinetics, from Moscow State University. In the late 1970s he worked at Harvard University; he was offered a contract to keep working there but the USSR government would not allow him to take it and he remained in the USSR. From 1979 to 1981 he was professor in the department of chemical enzymology at Moscow State University.[1]

From 1981 to 1990, he was professor and head of the Carbohydrates Research Laboratory at the A.N. Bach Institute of Biochemistry, USSR Academy of Sciences.[2] In the winter of 1982/1983 he became the first person behind the Iron Curtain who was allowed by the government of the USSR to use the computer network that later became the Internet, in order for him to represent the USSR in a conference hosted on the network; he used an x.25-connected computer at a Moscow institute called VNIIPAS.[3] He said that he developed methods to use enzymes to convert cotton plant waste products into glucose and by 1983 a pilot plant had been built in the USSR to test these methods.[4] He was awarded top Russian prizes in science and technology field: the Lenin Komsomol Prize in 1978 and the USSR State Prize in 1984.[1] In 1989 he was made a fellow of the World Academy of Art and Science.[5] In 2014 he became Foreign Member of the National Academy of Sciences of Georgia.[6]

Klyosov immigrated to the US in 1989[7] after Mikhail Gorbachev came to power,[3] and from 1990 to 1998 he was a visiting professor of biochemistry at the Center for Biochemical and Biophysical Sciences at Harvard Medical School.[2]

In 1991 he started a consulting business called MIR International.[8] [9]

From 1996 to 2006 Klyosov worked at a subsidiary of Kadant, where he applied enzymology to processing of waste products from the paper-making industry, and following advice from a friend in the plastics industry, helped create a business that used cellulose granules as filler material for plastic composite products.[10] [11]

In 2001 he helped found Pro-Pharmaceuticals, a company that was formed to use enzymes to add carbodydrates to existing cancer drugs to make them work better, and was caught up in scandal in 2004 when the company's investors accused its CEO of misrepresenting his role in the company.[12] He joined the company as Chief Scientific Officer in 2006.[10] Pro-Pharmaceuticals named a new CEO in March 2011,[13] and gave Klyosov a one-year contract to continue as CSO the same month.[14] The company was renamed as Galectin Therapeutics in May 2011.[15] He then became a member of the company's scientific advisory board.[2]

From 2008[16] Klyosov is also known as the author of what he calls "DNA genealogy", aimed to synthesize biology, anthropology, archaeology and linguistics and to implement methods of chemical kinetics in genetics.[17] [18] Klyosov described his "DNA genealogy" as a "patriotic science" and between 2010 and 2016 published 10 books in this field. In some of his writings Klyosov tried to refute the Out of Africa hypothesis and proposed his alternative Into Africa theory[19] with "outlandish claims" that the human species originated in Northern Russia.[17] A 2015 open letter from scientists in various fields said that his writing could fuel hatred “attracting readers whose nationalist and political ambitions are not satisfied with the world’s scientific body of knowledge.” Klyosov responded saying that they were members of a "fifth column".[20] "DNA genealogy" has been described as pseudoscience and "DNA demagoguery”.[21] [22] [23]

Klyosov is the founder and president of the Academy of DNA Genealogy[17] and self-publishes its proceedings via Lulu.[24]

In 2013 Klyosov became editor-in-chief of the journal Advances in Anthropology, published by Scientific Research Publishing.[17] [25]

Publications

Books in English

Books in Russian

Enzymology

Publications on "DNA genealogy"

External links

Notes and References

  1. Web site: Клёсов Анатолий Алексеевич = Klyosov Anatoly Alekseyevich. Летопись Московского университета. Аналитическая служба МГУ. Moscow. ru. https://web.archive.org/web/20170118163816/http://letopis.msu.ru/peoples/4652. 2017-01-18. dead.
  2. Web site: Galectin Therapeutics Advisory Board . 16 October 2014 . https://web.archive.org/web/20141121003843/http://galectintherapeutics.com/who-we-are/scientific-advisory-board/ . 2014-11-21 . dead .
  3. Web site: Internet-Pionier Kljosow: Genosse Online. 22 October 2010. SPIEGEL ONLINE. 15 October 2014.
  4. . Russians catch the nu-food bug . New Scientist . 26 May 1983 . 543 .
  5. Web site: World Academy of Art and Science . 2014-10-17 . https://web.archive.org/web/20141021225651/http://www.worldacademy.org/content/anatole-klyosov . 2014-10-21 . dead .
  6. Web site: Georgian National Academy of Sciences, Foreign Members .
  7. News: Профессор МГУ и Гарварда Анатолий Клесов: Генетика показала - отличий русских от украинцев вы не найдёте . Anatoly Klyosov, Professor of Moscow State University and of Harvard: Genetics Show That You Cannot Find Differences Between Russians And Ukrainians . Alekhina . Yuliya . 2016-05-27 . . ru . https://web.archive.org/web/20160528181910/http://www.kp.ru/daily/26535.7/3551840/. 2016-05-28. dead.
  8. Web site: Business Entity Summary for: MIR INTERNATIONAL, INC. . Massachusetts Secretary of the Commonwealth . 2016-06-22.
  9. Web site: Annual report: MIR INTERNATIONAL, INC. . Massachusetts Secretary of the Commonwealth . 2016-06-22 .
  10. Web site: Press Release: Pro-Pharmaceuticals Announces the Appointment of Anatole Klyosov, Ph.D., D.Sc. as Chief Scientist.. Pro-Pharmaceuticals via the Free Online Library. January 13, 2006.
  11. News: Schut. Jan H.. From Paper-Mill Sludge to Plastic Decking . Plastics Technology. October 2004.
  12. News: Krasner. Jeffrey. David Platt wants to cure cancer. Can his company avoid life support?. Boston Globe. March 14, 2004.
  13. Web site: Press Release: Pro-Pharmaceuticals Names Peter G. Traber, M.D., Former Glaxosmithkline Chief Medical Officer & President Emeritus Of Baylor College Of Medicine, President & Chief Executive Officer (Nasdaq:Galt). Galectin Therapeutics. March 9, 2011.
  14. Web site: Form 8-K, Exhibit Exhibit 10.1: Amended Employment Agreement dated 03/31/2011 between the Co.and Anatole Klyosov. SEC Edgar. April 6, 2011. See 8-K index page
  15. News: Lang. Michelle. Pro-Pharmaceuticals renames to Galectin Therapeutics. Boston Business Journal. May 26, 2011.
  16. Web site: Lebedev . V. P. .

    ru:Лебедев, Валерий Петрович

    . 2013-02-03 . Праславяне на слонах покоряют мир (Стеб Задорнова и наука Клесова). Protoslavs on Elephants Conquer the World (Zadornov's Banter and Klyosov's Science) . ru . . 2017-01-09 . Шел 2008 г, начало карьеры Клесова с его наукой про ДНК-генеалогию = It was 2008, the beginning of Klyosov's career with his science about DNA-genealogy..
  17. Web site: ДНК-демагогия Анатолия Клёсова. Balanovskaya. E. V.. Borinskaya. S. A.. 2015-01-13. TrV-Science. ru. Anatoly Klyosov's DNA demagoguery. Buzhilova. A. P.. Volkov. V. G.. Gerasimova. M. M.. Godina. E. Z.. Dubova. N. A.. Dybo. A. V.. Episkoposyan. L. M.. 1. Tyotushkin. E. Ya.. Khartanovich. V. I.. Chistov. Yu. K.. Yablonsky. Schnirelmann. V. A.. Victor Schnirelmann. Yusupov. Yu. M.. Sokolov. L. T.. A. V.. D. V.. L. S.. Anna Vladimirovna Dybo. Kasyan. A. S.. Kashibadze. V. F.. Klejn. Leo Klejn. I. V.. Kozintsev. A. G.. Kurbatova. Markina. N. V.. Pezhemsky. Perevozchikov. O. L..
  18. Web site: Balanovsky. O. P.. Y-хромосома как инструмент реконструкции происхождения тюркоязычных популяций Кавказа и Евразии: научные и антинаучные подходы . Y-chromosome as a tool for the reconstruction of the origin of the Turkic-speaking populations of the Caucasus and Eurasia: scientific and unscientific approaches (presentation at the conference "Ethnogenesis, history, language and culture of Karachai-Balkar people", 29 Nov 2014) . ru . . 2017-01-08.
  19. Web site: Problematical theories . UCL, Molecular and Cultural Evolution Lab . 2016-10-22 . 2016-10-22 . https://web.archive.org/web/20161022153220/https://www.ucl.ac.uk/mace-lab/debunking/theories . dead .
  20. News: Antonova . Maria . Putin's Great Patriotic Pseudoscience . Foreign Policy . November 29, 2016.
  21. Book: Balanovsky, O. P.. Лженаучные дискуссии . Pseudoscientific discussions . Генофонд Европы. Gene pool of Europe . ru . KMK Scientific Press . 2015 . 64–66 . 9785990715707.
  22. Web site: Balanovskaya . E. V. . Borinskaya. S. A. . Buzhilova. A. P.. Volkov. V. G.. Gerasimova. M. M.. Godina. E. Z.. Dubova. N. A.. Dybo. A. V.. Anna Vladimirovna Dybo. Episkoposyan. L. M.. Kasyan. A. S.. Kashibadze. V. F.. Klejn. L. S.. Leo Klejn . Kozintsev. A. G.. Kurbatova. O. L.. Markina. N. V.. Pezhemsky. D. V.. Perevozchikov. I. V.. Sokolov. A. V.. Tyotushkin. E. Ya.. Khartanovich. V. I.. Chistov. Yu. K.. Schnirelmann . V. A.. Victor Schnirelmann . Yusupov. Yu. M.. Yablonsky. L. T.. 1 . 2015-01-13. ДНК-демагогия Анатолия Клёсова. Anatoly Klyosov's DNA demagoguery . ru . TrV-Science.
  23. Book: Klein, L. S. . Leo Klejn . Опасная ДНК-демагогия Клёсова . Klyosov's dangerous DNA demagoguery . http://klnran.ru/wp-content/uploads/2015/05/BVZN_15.pdf#page=28 . Aleksandrov . E. B. . Efremov . Yu. N.. В защиту науки . In defense of science . ru . Moscow . Nauka . 2015 . . 29–49 . 978-5-02-039148-2. 2016-04-26.
  24. Book: Klein, L. S. . Leo Klejn . Происхождение славян, версия биохимическая . The origin of the Slavs, version biochemical . Российский археологический ежегодник N 5. Russian Archaeological Yearbook No 5. ru . 2015 . 651–664 .
  25. Web site: Beall . Jeffrey . Jeffrey Beall . 2014-10-02 . An Editorial Board Mass-Resignation — from an Open-Access Journal . dead . https://web.archive.org/web/20141018061921/http://scholarlyoa.com/2014/10/02/an-editorial-board-mass-resignation-from-an-open-access-journal/ . 2014-10-18 . 2015-01-08 . Scholarly Open Access.

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