Amygdalin beta-glucosidase explained

amygdalin β-glucosidase
Ec Number:	3.2.1.117
Cas Number:	51683-43-3
Go Code:	0047668

The enzyme amygdalin β-glucosidase catalyzes the following chemical reaction:

(R)-amygdalin + H₂O

\rightleftharpoons (R)-prunasin + D-glucose

Thus, the two substrates of this enzyme are (R)-amygdalin and H₂O, whereas its two products are (R)-prunasin and D-glucose.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is amygdalin beta-D-glucohydrolase. Other names in common use include amygdalase, amygdalinase, amygdalin hydrolase, and amygdalin glucosidase.

It can be completely inhibited by the action of Glucono-δ-lactone at 1 mM concentration.^[1]

References

• Kuroki G, Lizotte PA, Poulton JE . 1984 . Catabolism of (R)-Amygdalin and (R)-Vicianin by Partially Purified β-Glycosidases from Prunus serotina Ehrh. and Davallia trichomanoides . Z. Naturforsch. C . 39 . 232–239 .

Notes and References

1. Petruccioli . M. . Brimer . L. . Cicalini . A. R. . Federici . F. . 3 . Production and Properties of the Linamarase and Amygdalase Activities of Penicillium aurantiogriseum P35 . Bioscience, Biotechnology, and Biochemistry . 63. 5 . 805–812 . 1999 . 10380623 . 10.1271/bbb.63.805 . free .