Aminocandin Explained

Aminocandin is an echinocandin antifungal. It works by targeting the glucan in fungal cell walls.[1] [2]

Notes and References

  1. Andes D, Marchillo K, Lowther J, Bryskier A, Stamstad T, Conklin R . In vivo pharmacodynamics of HMR 3270, a glucan synthase inhibitor, in a murine candidiasis model . Antimicrobial Agents and Chemotherapy . 47 . 4 . 1187–92 . April 2003 . 12654645 . 152480 . 10.1128/aac.47.4.1187-1192.2003 .
  2. Brzankalski GE, Najvar LK, Wiederhold NP, Bocanegra R, Fothergill AW, Rinaldi MG, Pattterson TF, Graybill JR . 6 . Evaluation of aminocandin and caspofungin against Candida glabrata including isolates with reduced caspofungin susceptibility . The Journal of Antimicrobial Chemotherapy . 62 . 5 . 1094–100 . November 2008 . 18658194 . 2721694 . 10.1093/jac/dkn304 .

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