Aminoadipate-semialdehyde dehydrogenase explained

Aminoadipate-semialdehyde dehydrogenase is a protein that in humans is encoded by the AASDH gene.^[1]

Function

This gene encodes a member of the non-ribosome peptide synthetase (NRPS) enzyme family. The encoded protein contains an AMP-binding domain, PP-binding (phosphopantetheine, or pantetheine 4'phosphate-binding) domain and the Pyrrolo-quinoline quinon (PQQ) binding domain. The protein is expressed in several adult tissues.

Further reading

• Wang L, Jil C, Xu Y, Xu J, Dai J, Wu Q, Wu M, Zou X, Sun L, Gu S, Xie Y, Mao Y . Cloning and characterization of a novel human homolog* of mouse U26, a putative PQQ-dependent AAS dehydrogenase . Mol. Biol. Rep. . 32 . 1 . 47–53 . 2005 . 15865210 . 10.1007/s11033-003-2716-4. 26141158 .

Notes and References

1. Web site: Entrez Gene: Aminoadipate-semialdehyde dehydrogenase. 2017-01-02.