| Ambrogio Portalupi | |
| Fullname: | Ambrogio Portalupi |
| Birth Date: | 1943 1, df=yes |
| Birth Place: | Marcignago, Italy |
| Death Place: | Pavia, Italy |
| Discipline: | Road |
| Role: | Rider |
| Proyears1: | 1965 |
| Proyears2: | 1966–1967 |
| Proyears3: | 1968 |
| Proyears4: | 1969–1970 |
| Proyears5: | 1971 |
| Majorwins: | Tour de Suisse (1966) |
Ambrogio Portalupi (25 January 1943 – 5 January 1987) was an Italian racing cyclist. He won the 1966 Tour de Suisse and rode the Tour de France in 1965, 1967 and 1970.