Amanda Paulovich Explained

Amanda Paulovich
Alma Mater:	Carnegie Mellon University University of Washington
Thesis Title:	The Regulation of S Phase Progression Rate in Yeast in Response to DNA Damage
Thesis Year:	1996
Doctoral Advisor:	Leland H. Hartwell
Awards:	HUPO Distinguished Achievement in Proteomic Sciences Award
Field:	Biology
Work Institutions:	Fred Hutchinson Cancer Research Center

Amanda Grace Paulovich is an oncologist, and a pioneer in proteomics using multiple reaction monitoring mass spectrometry to study tailored cancer treatment.

Education

Paulovich received a BS in Biological Sciences from Carnegie Mellon University in 1988,^[1] a PhD in Genetics from University of Washington in 1996, under the direction of Leland Hartwell.^[2] She also received a MD from University of Washington in 1998.^[3] Follow her residency in Internal Medicine at Massachusetts General Hospital, she also completed a Postdoctoral Fellowship in Computational Biology at the Massachusetts Institute of Technology Whitehead Center for Genomic Research in 2003, and a Fellowship in Medical Oncology at the Dana Farber Cancer Institute in 2004.^[4]

Career

Paulovich is a Professor in Clinical Research, an Aven Foundation Endowed Chair, and the Director of Early Detection Initiative at the Fred Hutchinson Cancer Research Center.^{[5] [6]} She was inducted to the American Society for Clinical Inviestigation in 2012.^[7]

Paulovich is an expert in proteomics.^[8] Her targeted proteomics method uses multiple reaction monitoring mass spectrometry to target cancer biomarkers with ongoing clinical trials,^[9] and was named Method of the Year in 2012 by Nature Methods.^{[10] [11]} She founded Precision Assays in 2016,^[12] whose rights to targeted assays were acquired by CellCarta in 2022.^{[13] [14]}

Awards

• 2014 Life Science Innovation Northwest Woman to Watch in Life Science Award ^{[15] [16]}
• 2015 Human Proteome Organization (HUPO) Distinguished Achievement in Proteomic Sciences Award^{[17] [18]}

Patent applications

• Identification and use of biomarkers for detection and quantification of the level of radiation exposure in a biological sample (2011) US 20130052668 A1
• Compositions and methods for reliably detecting and/or measuring the amount of a modified target protein in a sample (2011) US 20130052669 A1

References

1. Web site: Amanda Paulovich, M.D., Ph.D. . 2022-06-06 . Fred Hutch . en.
2. Web site: UW Genome Sciences: Alumni . 2022-06-06 . www.gs.washington.edu.
3. Web site: Alumni Directory Medical Scientist Training Program . 2022-06-06.
4. Web site: Doctors Dr. Amanda G. Paulovich MD . June 6, 2022 . U.S. News & World Report.
5. Web site: September 1, 2004 . MCS Alumna Develops New Technologies for Early Cancer Detection . June 6, 2022 . Carnegie Mellon University Carnegie Mellon Today Archives.
6. Web site: Pittsburgh . A. Carnegie Mellon University Publication 5000 Forbes Avenue . Pa 15213268-2000 . MCS Alumna Develops New Technologies for Early Cancer Detection . 2022-06-06 . Carnegie Mellon Today . en.
7. Web site: The American Society for Clinical Investigation . 2022-06-08 . en-US.
8. Web site: Interviewer List Biocompare: The Buyer's Guide for Life Scientists . 2022-06-08 . www.biocompare.com.
9. Web site: CPTAC Contributes to the Identification of a Novel Pharmacodynamic Biomarker for Clinical Trial Use Office of Cancer Clinical Proteomics Research . 2022-06-08 . proteomics.cancer.gov . en.
10. Web site: Beyond genomics: Using proteomics to target tumors . 2022-06-08 . ScienceDaily . en.
11. Web site: 2017-02-06 . Fred Hutch's Paulovich lab to lead protein assay work for Beau Biden Cancer Moonshot . 2022-06-08 . American Association for the Advancement of Science (AAAS) EurekAlert! Archive.
12. Web site: PRECISION ASSAYS, LLC :: Washington (US) :: OpenCorporates . 2022-06-08 . opencorporates.com.
13. Web site: CellCarta Acquires Next-Generation Immuno-MRM Assays from Precision Assays . 2022-06-08 . CellCarta . en-CA.
14. Web site: CellCarta . CellCarta expands it proteomics portfolio with the acquisition of next-generation immuno-MRM assays from Precision Assays . 2022-06-08 . www.newswire.ca . en.
15. Web site: Pappu recognized as 'woman to watch' in life science . 2022-06-06 . WSU Insider . en-US.
16. Web site: MSACL-Paulovich . 2022-06-06 . www.msacl.org.
17. Web site: HUPO - Past Award Recipients . 2022-06-06 . www.hupo.org.
18. Web site: 2015-09-22 . SCIEX Partners with the Paulovich Lab at Fred Hutchinson Cancer Research Center to Advance Cancer Research Reproducibility . 2022-06-06 . www.businesswire.com . en.