| Alto Sermenza | |
| Coordinates: | 45.8667°N 12°W |
| Region: | Piedmont |
| Province: | Vercelli (VC) |
| Frazioni: | Rimasco, Rima San Giuseppe |
| Mayor: | Giuliana Marone |
| Area Total Km2: | 60.33 |
| Population Footnotes: | [1] |
| Population Total: | 160 |
| Population As Of: | 31 December 2016 |
| Elevation M: | 906 |
| Postal Code: | 13026 |
| Area Code: | 0163 |
Alto Sermenza is a comune (municipality) in the Province of Vercelli in the Italian region Piedmont, established on 1 January 2018 by the merger of the Rima San Giuseppe and Rimasco, in Valsesia.