Alphonse Desjardins (politician) should not be confused with Alphonse Desjardins (co-operator).
| Honorific-Prefix: | The Honourable |
| Alphonse Desjardins | |
| Honorific-Suffix: | PC |
| Order: | 22nd Mayor of Montreal |
| Term Start: | 1893 |
| Term End: | 1894 |
| Predecessor: | James McShane |
| Successor: | Joseph-Octave Villeneuve |
| Constituency Mp2: | Hochelaga |
| Parliament2: | Canadian |
| Predecessor2: | Louis Beaubien |
| Successor2: | Séverin Lachapelle |
| Term Start2: | 1874 |
| Term End2: | 1892 |
| Office3: | Senator for De Lorimier, Quebec |
| Appointed3: | John Abbott |
| Predecessor3: | Alexandre Lacoste |
| Successor3: | François Béchard |
| Term Start3: | 1892 |
| Term End3: | 1896 |
| Office4: | Minister of Militia and Defence |
| Term Start4: | 15 January 1896 |
| Term End4: | 27 April 1896 |
| Primeminister4: | Mackenzie Bowell |
| Predecessor4: | Mackenzie Bowell |
| Successor4: | David Tisdale |
| Birth Date: | 1841 5, df=yes |
| Birth Place: | Terrebonne, Province of Canada |
| Death Place: | Terrebonne, Quebec, Canada |
| Profession: | businessman, journalist, lawyer |
Alphonse Desjardins, PC (6 May 1841 - 4 June 1912) was born in Terrebonne, Canada East, and was mayor of Montreal from 1893 to 1894 and later a Canadian cabinet minister. He married Virginie Paré in 1864 and remarried Hortense Barsalou in 1880.
He was a lawyer, journalist, businessman and politician. He owned a tile factory and participated in the founding of the Banque Jacques-Cartier, which later became part of the National Bank of Canada. He represented the riding of Hochelaga in the House of Commons for 18 years, serving as a cabinet minister and Minister of Militia and Defence for a few months at the end of the Mackenzie Bowell government and then the short-lived Tupper government in 1896. He was named a senator in 1892. He became mayor of Montreal from 1893 - 1894. For a time he held all three posts (member of the House of Commons, Senator, mayor) simultaneously.
In 1872, he was created a Knight of the Order of Pius IX in acknowledgment of his services to the Catholic Church.