Alpha-seco-amyrin synthase explained

α-seco-amyrin synthase
Ec Number:	5.4.99.52

α-seco-amyrin synthase is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, alpha-seco-amyrin-forming).^[1] This enzyme catalyses the following chemical reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene

\rightleftharpoons alpha-seco-amyrin

The enzyme from Arabidopsis thaliana is multifunctional.

Notes and References

1. Shibuya M, Xiang T, Katsube Y, Otsuka M, Zhang H, Ebizuka Y . Origin of structural diversity in natural triterpenes: direct synthesis of seco-triterpene skeletons by oxidosqualene cyclase . Journal of the American Chemical Society . 129 . 5 . 1450–5 . February 2007 . 17263431 . 10.1021/ja066873w .