Alpha-guaiene synthase explained

α-guaiene synthase
Ec Number:	4.2.3.87

α-Guaiene synthase (EC 4.2.3.87, PatTps177 (gene)) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, α-guaiene-forming).^{[1] [2]} This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate

\rightleftharpoons α-guaiene + diphosphate

This enzyme requires Mg²⁺.

Notes and References

1. Deguerry F, Pastore L, Wu S, Clark A, Chappell J, Schalk M . The diverse sesquiterpene profile of patchouli, Pogostemon cablin, is correlated with a limited number of sesquiterpene synthases . Archives of Biochemistry and Biophysics . 454 . 2 . 123–36 . October 2006 . 16970904 . 10.1016/j.abb.2006.08.006 .
2. Kumeta Y, Ito M . Characterization of δ-guaiene synthases from cultured cells of Aquilaria, responsible for the formation of the sesquiterpenes in agarwood . Plant Physiology . 154 . 4 . 1998–2007 . December 2010 . 20959422 . 2996018 . 10.1104/pp.110.161828 .