Alpha-eudesmol synthase explained

α-eudesmol synthase
Ec Number:	4.2.3.85

α-Eudesmol synthase (EC 4.2.3.85) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (α-eudesmol-forming).^[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate + H₂O

\rightleftharpoons α-eudesmol + diphosphate

The recombinant enzyme from ginger (Zingiber zerumbet) gives β-eudesmol, 10-epi-γ-eudesmol, α-eudesmol and aristolene.

Notes and References

1. Yu F, Harada H, Yamasaki K, Okamoto S, Hirase S, Tanaka Y, Misawa N, Utsumi R . Isolation and functional characterization of a β-eudesmol synthase, a new sesquiterpene synthase from Zingiber zerumbet Smith . FEBS Letters . 582 . 5 . 565–72 . March 2008 . 18242187 . 10.1016/j.febslet.2008.01.020 .