Allophanate hydrolase explained
| allophanate hydrolase |
| Ec Number: | 3.5.1.54 |
| Cas Number: | 79121-96-3 |
| Go Code: | 0004039 |
In enzymology, an allophanate hydrolase is an enzyme that catalyzes the chemical reaction
allophanate + 3 H2O + H+
2 HCO
3− + 2 NH
4+Thus, the two substrates of this enzyme are allophanate (urea-1-carboxylate or N-carbamoylcarbamate) and H2O, whereas its two products are HCO3− and NH4+.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is urea-1-carboxylate amidohydrolase. This enzyme is also called allophanate lyase. This enzyme participates in urea cycle and metabolism of amino groups and atrazine degradation.
See also
References
- Maitz GS, Haas EM, Castric PA . 1982 . Purification and properties of the allophanate hydrolase from Chlamydomonas reinhardii . Biochim. Biophys. Acta . 714 . 486 - 491 . 10.1016/0304-4165(82)90158-1.
- Roon RJ, Levenberg B . 1972 . Urea amidolyase. I. Properties of the enzyme from Candida utilis . J. Biol. Chem. . 247 . 4107 - 13 . 4556303 . 13 .
- Sumrada RA, Cooper TG . 1982 . Urea carboxylase and allophanate hydrolase are components of a multifunctional protein in yeast . J. Biol. Chem. . 257 . 9119 - 27 . 6124544 . 15 .
- Kanamori T, Kanou N, Kusakabe S, Atomi H, Imanaka T . 2005 . Allophanate hydrolase of Oleomonas sagaranensis involved in an ATP-dependent degradation pathway specific to urea . FEMS Microbiol. Lett. . 245 . 61 - 5 . 15796980 . 10.1016/j.femsle.2005.02.023 . 1 . free .
