| Allene Jeanes | |
| Birth Name: | Allene Rosalind Jeanes |
| Birth Date: | 19 July 1906 |
| Birth Place: | Waco, Texas, U.S. |
| Death Place: | Urbana, Illinois, U.S. |
| Education: | University of Illinois at Urbana-Champaign |
| Occupation: | Chemist |
| Known For: | Developing Dextran |
Allene Rosalind Jeanes (July 19, 1906 – December 11, 1995) was an American chemist whose pioneering work significantly impacted carbohydrate chemistry. Born in 1906 in Texas, Jeanes' notable contributions include the development of Dextran, a lifesaving blood plasma substitute used in the Korean and Vietnam wars, and Xanthan gum, a polysaccharide commonly used in the food, cosmetics, and pharmaceutical industries. Jeanes' innovations have had a lasting influence on medical treatments and everyday consumer products, highlighting her role as a key figure in applied carbohydrate science.[1] Her achievements earned her numerous accolades, including being the first woman to receive the Distinguished Service Award from the U.S. Department of Agriculture.
Jeanes was born July 19, 1906, in Waco, Texas, to Viola (Herring) and Largus Elonzo Jeanes, a switchman and later a yardmaster for the Cotton Belt Route of the St. Louis Southwestern Railway. Allene graduated with honors from Waco High School in 1924.[2] In 1928, she received a bachelor's degree from Baylor University and graduated summa cum laude; in 1929, Jeanes obtained a master's degree in organic chemistry from the University of California, Berkeley.[3] She was Jewish.
From 1930 to 1935, Jeanes was employed as the head science teacher at Athens College in Athens, Alabama. From 1936 to 1937, she held a position as chemistry instructor at the University of Illinois.[3] She received her PhD in organic chemistry from University of Illinois in 1938, after working with Roger Adams.[4]
In 1938, Dr. Jeanes decided to accept a position at the National Institutes of Health in Washington D.C. And, from 1938 to 1940, Jeanes served as a corn industries research foundation fellow for the National Institutes of Health (NIH) with Claude Hudson and worked at the National Bureau of Standards with Horace S. Isbell.In 1941 she joined Roy L. Whistler at the U.S. Department of Agriculture’s Northern Regional Research Lab (NRRL) in Peoria, Illinois, as a chemical researcher. She worked there until 1976.[5] Jeanes is credited with "a prominent role in making NRRL a world-class center for applied carbohydrate science".
Jeanes' area of research was natural polysaccharides, including starch (found in wheat, corn, rice, and potatoes), cellulose (found in cotton, wood, and paper), and dextran. Jeanes was able to isolate dextran-producing bacteria from samples of bacteria-contaminated root beer supplied by a local Peoria company.[5] This discovery was the basis for development of a mass production process for dextran, and its use in a dextran-based blood plasma extender. This plasma substitute was used by medical personal in the Korean and Vietnam wars. It was believed that using this sort of substance would keep someone who had lost a great deal of blood alive longer.[6] So, the United States began using dextran to treat injured soldiers. As a result of her work, Jeanes was the first woman to receive the Distinguished Service Award given by the Department of Agriculture, in 1953.[7] She was also awarded the Garvan Medal in 1956.[8]
Jeanes was also part of the team that developed xanthan gum. Xanthan gum, derived from Xanthomonas campestris bacteria, completely revolutionized food processing due to its unique thickening and stabilizing properties.[9] It's extensively used in products such as salad dressings, sauces, and baked goods to maintain texture and consistency. In the cosmetics industry, xanthan gum improves the texture of creams and lotions, making them more appealing to consumers.
In medicine, xanthan gum plays a role in creating more appetizing and stable pharmaceutical products. It's also essential in gluten-free baking, providing a substitute that mimics the texture and properties of gluten, greatly benefiting those with gluten intolerances or celiac disease.[9]
Moreover, xanthan gum has applications beyond these industries. It is used in the oil and gas sector for drilling operations, demonstrating the versatility of Jeanes' innovation. The environmental friendliness of xanthan gum, as it is a biodegradable and non-toxic substance, aligns perfectly with current sustainable and environmentally friendly trends, making it a preferred ingredient in various sectors.[9]
Overall, Jeanes' work in this development has had a far-reaching impact, contributing significantly to advancements in food science, cosmetics, medicine, and even energy, thereby enhancing various aspects of everyday life. Her innovation and contributions are still in use today in many ways.
In her last published paper, "Immunological and Related Interactions with Dextrans Reviewed in Terms of Improved Structural Information," which was published in 1986, Jeanes shows her dedication to her work.[2]
Over the course of her entire career, Allene Jeanes was awarded ten patents and produced sixty publications.[6] These were all related to her work and discoveries. She was ultimately honored with a plethora of awards.
She was a member of the American Chemical Society, Sigma Xi, and Iota Sigma Pi.[10]
Jeanes died on December 11, 1995 in Urbana, Illinois.[11] She was 89 years old.[6]