Fexofenadine/pseudoephedrine explained

Type:combo
Component1:Fexofenadine
Class1:Antihistamine
Component2:Pseudoephedrine
Class2:Nasal decongestant
Tradename:Allegra-D
Dailymedid:Fexofenadine hydrochloride and pseudoephedrine hydrochloride
Pregnancy Au:B2
Routes Of Administration:By mouth
Atc Prefix:R01
Atc Suffix:BA52
Legal Au:S3
Legal Ca:OTC
Legal Ca Comment:[1]
Legal Us:OTC
Legal Us Comment:[2] [3]
Kegg:D10252

Fexofenadine/pseudoephedrine, sold under the brand name Allegra-D among others, is a fixed-dose combination medication used for the treatment of nasal congestion and other symptoms of allergies[4] and the common cold. It contains fexofenadine, as the hydrochloride, an antihistamine; and pseudoephedrine, as the hydrochloride, a nasal decongestant.

In 2021, it was the 279th most commonly prescribed medication in the United States, with more than 800,000 prescriptions.[5] [6]

Notes and References

  1. Web site: Allegra-D Product information . . 25 April 2012 . 2 June 2022.
  2. Web site: Allegra-D Allergy and Congestion- fexofenadine hydrochloride and pseudoephedrine hydrochloride tablet, film coated, extended release . DailyMed . 3 December 2020 . 2 June 2022.
  3. Web site: Allegra-D Allergy and Congestion- fexofenadine hydrochloride and pseudoephedrine hydrochloride tablet, film coated, extended release . DailyMed . 30 August 2021 . 2 June 2022.
  4. Mansfield LE . Once-daily immediate-release fexofenadine and sustained-release pseudoephedrine combination: a new treatment option for allergic rhinitis . Expert Opinion on Pharmacotherapy . 7 . 7 . 941–51 . May 2006 . 16634716 . 10.1517/14656566.7.7.941 . 23165002 .
  5. Web site: The Top 300 of 2021 . ClinCalc . 14 January 2024 . 15 January 2024 . https://web.archive.org/web/20240115223848/https://clincalc.com/DrugStats/Top300Drugs.aspx . live .
  6. Web site: Fexofenadine; Pseudoephedrine - Drug Usage Statistics . ClinCalc . 14 January 2024.