| All-Ireland Senior B Hurling Championship | |
| Year: | 1981 |
| Country: | |
| Winners: | Antrim |
| Second: | London |
| Prev Season: | 1980 |
| Next Season: | 1982 |
The 1981 All-Ireland Senior B Hurling Championship was the eighth staging of Ireland's secondary hurling knock-out competition. Antrim won the championship, beating London 3–17 to 3–14 in the final at Fr. Healy Park, Loughguile.
First round
Quarter-final
Semi-finals
Home final
Final