| Ali Hikmet Ayerdem | |
| Honorific Suffix: | 1314-P. 16[1] |
| Birth Date: | 1877 |
| Birth Place: | Larissa, Ottoman Empire |
| Death Place: | Istanbul, Turkey |
| Placeofburial: | Zincirlikuyu Mezarlığı State Cemetery |
| Allegiance: |  Turkey |
| Serviceyears: | Ottoman Empire: 1899–1920 Turkey: January 28, 1921 – May 26, 1935 |
| Rank: | General |
| Commands: | Chief of Staff of the IV Corps, 49th Division, Izmir Railway 12th Division, Undersecretary of the Ministry of National Defense, II Corps, VI Corps |
| Battles: |
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| Laterwork: | Member of the GNAT (Bursa) Member of the GNAT (Gaziantep) |
Ali Hikmet Ayerdem (1877; Larissa – March 21, 1939; Istanbul) was an officer of the Ottoman Army and a general of the Turkish Army.