Ali Ertürk Explained

Ali Maximilian Ertürk
Education:2009–2014 Postdoctoral fellow, Genentech Inc2003–2009 Ph.D., Max–Planck–Institute of Neurobiology, Munich1998–2003 Bachelor of Science, Bilkent University, Ankara
Employer:2019–current Director, Helmholtz Munich, Institute for Tissue Engineering & Regenerative Medicine
Known For:Developing and combining unbiased & scalable technologies for better diagnostics and therapeutics, in particular DISCO whole organ/organism imaging.

Ali Maximilian Ertürk (born September 1980) is a neuroscientist, inventor, and artist living in Munich, Germany. He is the director of a new Helmholtz Institute on Tissue Engineering and Regenerative Medicine in Munich since July 2019 and professor at the medical faculty.[1] After his undergraduate study at Bilkent University in Ankara, he joined Max-Planck-Institute for Neurobiology for his PhD and Genentech Inc. for postdoctoral research.

His is known for invention of DISCO tissue transparency technology and deep learning based analysis of large 3D images in biomedicine.[2] [3] [4] [5] [6] [7] The methods collectively target to analyze cellular and molecular details of whole organs and bodies.[8] [9] [10] Ertürk is full (W3) Professor of the Ludwig Maximilian University of Munich[11] and affiliated also with the University of Rochester.[12] He also founded 2 biotechnology companies (Deep Piction and 1X1 Biotech) in 2022 with the aim of creating novel therapies to treat life-threatening illnesses such as cancer, Alzheimer's disease, and heart conditions.

Honors and awards

Source:[24]

Entrepreneurial life

Ali Ertürk is founder of 2 biotechnology companies called Deep Piction and 1X1 Biotech. Deep Piction is a biotechnology company that combines biomedical research, artificial intelligence, engineering, and drug delivery methods to accelerate the development of new treatments for deadly diseases[25] DEEP Piction GmbH | Handelsregisterauszug Bonitätsauskunft. The company's mission is to leverage the power of AI and other advanced technologies to improve the success rates of clinical trials and reduce the time it takes to develop new drugs.

One of Deep Piction's primary aims is to develop new methods to deliver drugs directly to correct cellular targets. By using AI to identify specific targets and design drug delivery systems, the company hopes to improve the efficacy and safety of new treatments. Additionally, Deep Piction is committed to reducing the use of animals in research by moving towards in silico models.

1X1 Biotech is another biotechnology company that uses AI to accelerate drug development. The company's mission is to discover and develop new treatments for diseases with high unmet medical needs, such as cancer and rare genetic disorders. 1X1 Biotech's approach combines machine learning, network biology, and high-throughput screening to identify promising drug candidates and optimize their efficacy.[26] [24]

One of 1X1 Biotech's primary aims is to improve the success rates of clinical trials by identifying biomarkers and patient subpopulations that are most likely to respond to a given treatment. By using AI to analyze large amounts of data from clinical trials, the company hopes to improve the precision of drug development and bring new treatments to patients faster.

Overall, Deep Piction and 1X1 Biotech are two promising biotechnology companies that are leveraging the power of AI and other advanced technologies to accelerate drug development and improve the success rates of clinical trials.

Art life

Ali Ertürk is also known for his landscape and cityscapes photographs.[27] [28] [29] He had photo art 3 exhibitions (2008 Munich, 2012 San Francisco, 2015 Munich).[30]

Notes and References

  1. Web site: Institutes / Research Units. www.helmholtz-muenchen.de. 2019-08-25.
  2. Ertürk. Ali. Mauch. Christoph P. Hellal. Farida. Förstner. Friedrich. Keck. Tara. Becker. Klaus. Jährling. Nina. Steffens. Heinz. Richter. Melanie. January 2012. Three-dimensional imaging of the unsectioned adult spinal cord to assess axon regeneration and glial responses after injury. Nature Medicine. 18. 1. 166–171. 10.1038/nm.2600. 22198277. 16100638 . 1546-170X.
  3. Ertürk. Ali. Becker. Klaus. Jährling. Nina. Mauch. Christoph P. Hojer. Caroline D. Egen. Jackson G. Hellal. Farida. Bradke. Frank. Sheng. Morgan. November 2012. Three-dimensional imaging of solvent-cleared organs using 3DISCO. Nature Protocols. 7. 11. 1983–1995. 10.1038/nprot.2012.119. 23060243. 2882746 . 1750-2799.
  4. Pan. Chenchen. Cai. Ruiyao. Quacquarelli. Francesca Paola. Ghasemigharagoz. Alireza. Lourbopoulos. Athanasios. Matryba. Paweł. Plesnila. Nikolaus. Dichgans. Martin. Hellal. Farida. October 2016. Shrinkage-mediated imaging of entire organs and organisms using uDISCO. Nature Methods. 13. 10. 859–867. 10.1038/nmeth.3964. 27548807. 3521504 . 1548-7105.
  5. Cai. Ruiyao. Pan. Chenchen. Ghasemigharagoz. Alireza. Todorov. Mihail I.. Foerstera. Benjamin. Zhao. Shan. Bhatia. Harsharan S.. Mrowka. Leander. Theodorou. Delphine. 2018-07-23. Panoptic vDISCO imaging reveals neuronal connectivity, remote trauma effects and meningeal vessels in intact transparent mice. bioRxiv. en. 374785. 10.1101/374785. free.
  6. Ertürk. Ali. Nedergaard. Maiken. Kerschensteiner. Martin. Menze. Bjoern. Liesz. Arthur. Bechmann. Ingo. Liebscher. Sabine. Steinke. Hanno. Benakis. Corinne. 2018-12-31. Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull–meninges connections. Nature Neuroscience. 22. 2. en. 317–327. 10.1038/s41593-018-0301-3. 30598527. 1546-1726. 6494982.
  7. Erturk. Ali. Zeidler. Reinhard. Menze. Bjoern. Garvalov. Boyan K.. Coronel. Javier. Reimer. Madita Alice. Ghasemi. Alireza. Neubeck. Bettina von. Gondi. Gabor. 2019-02-05. Deep learning reveals cancer metastasis and therapeutic antibody targeting in whole body. bioRxiv. en. 541862. 10.1101/541862. free.
  8. News: Seeing Through to a Mouse's Nervous System. Fleur. Nicholas St. 2016-08-22. The New York Times. 2018-03-22. 0362-4331.
  9. News: New Technique Shrinks, Makes Small Animals Transparent. Hernandez. Daniela. 2016-08-22. Wall Street Journal. 2018-03-22. 0099-9660.
  10. News: A 'revolutionary' new technology can turn mice clear — and might one day map your brain. Business Insider Deutschland. 2018-03-22. de.
  11. Web site: weingart . antonia . LMU . 2018-04-24 . research.isd-muc.de . en-US.
  12. Web site: Personnel - Nedergaard Lab - University of Rochester Medical Center. www.urmc.rochester.edu. en. 2018-04-24.
  13. Web site: MSCA PhD Funding – A Guide. www.FindAPhD.com.
  14. Web site: Sofja Kovalevskaja Award. www.humboldt-foundation.de.
  15. http://www.neuron-eranet.eu/_media/Plesnila.pdf
  16. http://icemed.helmholtz.de
  17. http://research.isd-muc.de/Acute_braininjury_PI.html
  18. Web site: ISD RESEARCH. weingart. antonia. research.isd-muc.de. en-US. 2018-04-24.
  19. Web site: Die Rückkehr der Superhirne. 2020-07-06. FOCUS Online. de. 2022-08-13. https://web.archive.org/web/20220813200814/https://www.focus.de/magazin/archiv/wissen-die-rueckkehr-der-superhirne_id_11274019.html. dead.
  20. Web site: Ali Ertürk. 2020-07-06. Cure Alzheimer's Fund.
  21. Web site: Press Release: SyNergy member Ali Ertürk receives ERC Consolidator Grant - Munich Cluster for Systems Neurology - LMU Munich. 2020-07-06. www.synergy-munich.de. en.
  22. Marx. Vivien. 2020-04-01. Ali Ertürk. Nature Methods. en. 17. 4. 357. 10.1038/s41592-020-0798-8. 32203390 . 1548-7105. free.
  23. Web site: Verleihung Rolf Becker-Preis 2020 - Medizinische Fakultät - LMU München. 2021-02-28. www.med.uni-muenchen.de. de.
  24. Web site: 1X1 Biotech GmbH, München Firmenauskunft . 2023-03-05 . firmeneintrag.creditreform.de.
  25. Web site: DEEP Piction GmbH, München Firmenauskunft . 2023-03-05 . firmeneintrag.creditreform.de.
  26. Web site: Redaktion . Elf Projektteams pitchen beim Life Science Pitch Day im IZB . 2023-03-05 . de-DE.
  27. Web site: Ali Ertürk. www.biochem.mpg.de. 2018-04-14.
  28. Web site: Ali Erturk. 500px.com. 2018-04-14.
  29. Web site: Ali Erturk Photography. www.facebook.com. 2018-04-14.
  30. News: Mit eigenen Augen. Martinsried. Annette Jäger. 2015-11-05. Süddeutsche Zeitung. With your own eyes. German. https://web.archive.org/web/20180327210617/http://www.sueddeutsche.de/muenchen/martinsried-mit-eigenen-augen-1.2723896. 2018-03-27. 2018-03-27.

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