| Honorific-Prefix: | Most Reverend |
| Alfonso Santillán Fajardo | |
| Bishop of Quito | |
| Church: | Catholic Church |
| Diocese: | Diocese of Quito |
| Term: | 1616–1620 |
| Predecessor: | Hernando de Arias y Ugarte |
| Successor: | Francisco Sotomayor |
| Death Date: | 15 Oct 1620 |
| Death Place: | Quito, Ecuador |
Alfonso Santillán Fajardo, O.P. (died 15 Oct 1620) was a Roman Catholic prelate who served as Bishop of Quito (1616–1620).[1] [2]
Alfonso Santillán Fajardo was ordained a priest in the Order of Preachers. On 23 Mar 1616, he was appointed during the papacy of Pope Paul V as Bishop of Quito. He served as Bishop of Quito until his death on 15 Oct 1620.