| Alexi Spann | |
| Fullname: | Alexandra Spann |
| Nicknames: | Alexi |
| Strokes: | Breaststroke |
| Club: | Longhorn Aquatics |
| Collegeteam: | University of Texas |
| Birth Date: | 21 October 1986 |
| Birth Place: | Austin, Texas, United States |
Alexandra ("Alexi") Spann (born October 21, 1986) is a female breaststroke swimmer from the United States, who won the gold medal in the women's 200m breaststroke event at the 2003 Pan American Games.
Spann is a native of Austin, Texas. Her father, Scott Spann Sr., is a six-time US swimming champion and won the bronze medal in the 200m individual medley race at the 1979 Pan American Games in San Juan, Puerto Rico. Her brother, Scott Spann Jr., was a member of the 2008 U.S. Olympic Team in the 200 m breaststroke.