| Type: | Cardinal |
| Honorific Prefix: | His Eminence |
| Alexandre José Maria dos Santos | |
| Honorific Suffix: | O.F.M. |
| Archbishop Emeritus of Maputo | |
| Church: | Roman Catholic Church |
| Archdiocese: | Maputo |
| See: | Maputo |
| Appointed: | 18 September 1976[1] |
| Retired: | 22 February 2003 |
| Predecessor: | Custódio Alvim Pereira |
| Successor: | Francisco Chimoio |
| Other Post: | Cardinal-Priest of San Frumenzio ai Prati Fiscali (1988–2021) |
| Ordination: | 25 June 1953 |
| Ordained By: | Manuel Gonçalves Cerejeira |
| Consecration: | 9 March 1975 |
| Consecrated By: | Agnelo Rossi |
| Cardinal: | 28 June 1988 |
| Created Cardinal By: | Pope John Paul II |
| Rank: | Cardinal-Priest |
| Birth Name: | Alexandre José Maria dos Santos |
| Birth Date: | 18 March 1924 |
| Birth Place: | Zavala, Mozambique |
| Death Place: | Maputo, Mozambique |
| Tomb: | --> |
| Partner: | --> |
| Previous Post: | Archbishop of Laurençco Marques (1974–76)[2] |
| Motto: | Servir e não ser servido ("To serve, not to be served") |
| Coat Of Arms: | Coat of arms of Alexandre Jose Maria dos Santos.svg |
Alexandre José Maria dos Santos (18 March 1924 – 29 September 2021) was a Mozambican Roman Catholic cardinal. He was the first native cardinal of Mozambique.
Dos Santos was born in Zavala, Mozambique. He studied in Nyasaland and Lisbon before being ordained a Roman Catholic priest in 1953, becoming the first black Mozambican to receive the distinction.[3] In 1973 he became the first African to run a seminary in Mozambique.[4] He was archbishop of Maputo, between 1975 and 2003. On 26 June 1988, he was created a cardinal by Pope John Paul II, and given the titular church of San Frumenzio ai Prati Fiscali.[5] He was instrumental in the peace process surrounding the end of the Mozambican Civil War. He did not participate in the conclaves of 2005 and 2013, because he was over the age limit by then.