Alexander Rudensky Explained

Alexander Rudensky (born August 21, 1956)^{[1] [2]} is an immunologist at Memorial Sloan Kettering Cancer Center known for his research on regulatory T cells and the transcription factor Foxp3.^[3]

Career

Rudensky received his Candidate of Sciences degree in 1986 from the Gabrichevsky Research Institute of Epidemiology and Microbiology, Moscow, and completed his postdoctoral work at the Yale School of Medicine.^[4] He is now the Chair of the Immunology Program and Director of the Ludwig Center at Memorial Sloan Kettering, as well as a professor at the Rockefeller University, Cornell University, Gerstner School of Graduate Studies, and Weill-Cornell Medical School.^[5]

In a 2003 paper, Rudensky and colleagues showed that Foxp3 programs regulatory T cell development. His lab continues to investigate the molecular mechanisms underlying regulatory T cell activity, and the role these cells play in autoimmunity, tumor immunity, and immunity to infections.^[6]

Awards

• 2012 Member of the National Academy of Sciences^[7]
• 2015 Member of the American Academy of Arts and Sciences^[8]
• 2015 William B. Coley Award^[9]
• 2017 Crafoord Prize in Polyarthritis^[10]
• 2018 Vilcek Prize in Biomedical Science

External links

• mskcc.org
• Fontenot . Jason D. . Rasmussen . Jeffrey P. . Williams . Luke M. . Dooley . James L. . Farr . Andrew G. . Rudensky . Alexander Y. . Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3 . Immunity . 22 . 3 . 329–41 . 2005 . 15780990 . 10.1016/j.immuni.2005.01.016 . free .

Notes and References

1. Web site: Rudensky, Alexander. Library of Congress. 13 September 2016.
2. Web site: JCI's Conversations with Giants in Medicine: Alexander Rudensky. Youtube. 14 September 2016. 22 August 2016.
3. Fontenot. Jason D.. Gavin. Marc A.. Rudensky. Alexander Y.. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nature Immunology. 1 April 2003. 4. 4. 330–336. 10.1038/ni904. 12612578. 3343021 . 1529-2908.
4. Web site: MSK center. Ludwig Cancer Research. 13 September 2016. https://web.archive.org/web/20180818214547/https://www.ludwigcancerresearch.org/location/msk-center. 18 August 2018. dead.
5. Web site: King. Christopher. The 2015 Thomson Reuters Citation Laureates. Thomson Reuters. 13 September 2016. https://web.archive.org/web/20150925071522/http://stateofinnovation.thomsonreuters.com/citation-laureates-2015. 25 September 2015. dead.
6. Web site: The Alexander Rudensky Lab. Memorial Sloan Kettering Cancer Center. 13 September 2016.
7. Web site: Alexander Rudensky. National Academy of Sciences. 13 September 2016.
8. Web site: Newly Elected Members, April 2015. American Academy of Arts and Sciences. 13 September 2016.
9. Web site: William B. Coley Award. Cancer Research Institute. 13 September 2016.
10. Web site: Polyarthritis - Crafoordprize. www.crafoordprize.se. 14 April 2017. en. 23 April 2018. https://web.archive.org/web/20180423033946/http://www.crafoordprize.se/prizesawarded/polyarthritis.4.2f692b3510dbfce339680009422.html. dead.