Aleksandra Radenovic Explained

Aleksandra Radenovic
Citizenship:Switzerland
Croatia
Website:https://lben.epfl.ch/
Education:Physics
Alma Mater:University of Zagreb
University of Lausanne
Thesis Title:Development of low temperature atomic force microscope for biological applications
Thesis Url:https://www.worldcat.org/oclc/85233283
Thesis Year:2003
Doctoral Advisor:Giovanni Dietler
Academic Advisors:Jan Liphardt
Discipline:Biological engineering
Biophysics
Nanofluidics
Microscopy
Cell biology
Workplaces:École Polytechnique Fédérale de Lausanne (EPFL)
Main Interests:Single molecule biophysics
Solid State Nanopores
2-D materials
Optical tweezers
Second-harmonic generation
Super-resolution microscopy

Aleksandra Radenovic (born in 1975 in Croatia) is a Swiss and Croatian biophysicist. Her research focuses on the development of experimental tools to study single-molecule biophysics. She is a professor of biological engineering at the École Polytechnique Fédérale de Lausanne (EPFL) and head of the Laboratory of Nanoscale Biology.[1] [2]

Career

Radenovic studied physics at the University of Zagreb, where she wrote her Master thesis on Raman spectroscopy of Beta-Carotene. She then joined Giovanni Dietler's Laboratory of Physics of Living Matter, then located at University of Lausanne, and in 2003, she graduated with a PhD on cryo atomic force microscopy.[3] [4] For postdoctoral studies she went to work at University of California, Berkeley with Jan Liphardt.[5] In 2008, she became an assistant professor at EPFL where she established the Laboratory of Nanoscale Biology. In 2015, she was promoted as an associate professor.

Research

Radenovic's area of research is the development of experimental techniques for the study of molecular and cell biology making use of biosensors and optical imaging. In particular, she is interested in single-molecule biophysics.[6] [7]

Her research follows three main trajectories. First, she employs nanopores applied on suspended 2D material membranes, standard silicon-nitride membranes, and in glass nanocapillaries to study and manipulate single molecules.[8] [9] [10] Then, Radenovic studies the function of single molecules, especially protein and nucleic acid interactions, via optical tweezers, optical wrench system, anti-Brownian electrokinetic trap, and a combination of nanopores or nanocapillaries with optical tweezers.[11] [12] [13] Finally, based on single molecule localization microscopy, she designs super-resolution optical microscopes to extract quantitative information on single molecules.[14] [15] [16]

Selected publications

External links

Notes and References

  1. Web site: 23 professors appointed at ETH Zurich and EPFL ETH-Board. 2020-09-22. www.ethrat.ch.
  2. Web site: Group members. 2020-09-22. www.epfl.ch. en-GB.
  3. Radenovic . Aleksandra . 2003 . Development of low temperature atomic force microscope for biological applications . 85233283 . 2022-06-06.
  4. Libioulle. Laurent. Radenovic. Alexandra. Bystrenova. Eva. Dietler. Giovanni. 24 January 2003. Low noise current-to-voltage converter and vibration damping system for a low-temperature ultrahigh vacuum scanning tunneling microscope. Review of Scientific Instruments. 74. 2. 1016–1021. 10.1063/1.1533100. 2003RScI...74.1016L. 0034-6748.
  5. Web site: Liphardt Lab. 2020-09-22. liphardtlab.stanford.edu.
  6. Web site: Aleksandra Radenovic. EPFL Online People Directory.
  7. Web site: Research Topics. 2020-09-23. www.epfl.ch. en-GB.
  8. Feng. Jiandong. Graf. Michael. Liu. Ke. Ovchinnikov. Dmitry. Dumcenco. Dumitru. Heiranian. Mohammad. Nandigana. Vishal. Aluru. Narayana R.. Kis. Andras. Radenovic. Aleksandra. 11 August 2016. Single-layer MoS2 nanopores as nanopower generators. Nature. en. 536. 7615. 197–200. 10.1038/nature18593. 27409806. 2016Natur.536..197F. 4447903. 0028-0836.
  9. Liu. Ke. Feng. Jiandong. Kis. Andras. Radenovic. Aleksandra. 25 March 2014. Atomically Thin Molybdenum Disulfide Nanopores with High Sensitivity for DNA Translocation. ACS Nano. en. 8. 3. 2504–2511. 10.1021/nn406102h. 24547924. 1936-0851.
  10. Macha. Michal. Marion. Sanjin. Nandigana. Vishal V. R.. Radenovic. Aleksandra. 30 July 2019. 2D materials as an emerging platform for nanopore-based power generation. Nature Reviews Materials. en. 4. 9. 588–605. 10.1038/s41578-019-0126-z. 2019NatRM...4..588M. 199466502. 2058-8437.
  11. Feng. Jiandong. Liu. Ke. Bulushev. Roman D.. Khlybov. Sergey. Dumcenco. Dumitru. Kis. Andras. Radenovic. Aleksandra. 21 September 2015. Identification of single nucleotides in MoS2 nanopores. Nature Nanotechnology. en. 10. 12. 1070–1076. 10.1038/nnano.2015.219. 26389660. 1505.01608. 2015NatNa..10.1070F. 8087282. 1748-3387.
  12. Kayci. Metin. Radenovic. Aleksandra. 12 November 2015. Single florescent [sic] nanodiamond in a three dimensional ABEL trap. Scientific Reports. en. 5. 1. 16669. 10.1038/srep16669. 2045-2322. 4642320. 26559890. 2015NatSR...516669K.
  13. Web site: Full Page Reload. 2020-09-23. IEEE Spectrum: Technology, Engineering, and Science News. en.
  14. Feng. Jiandong. Liu. Ke. Graf. Michael. Dumcenco. Dumitru. Kis. Andras. Di Ventra. Massimiliano. Radenovic. Aleksandra. 28 March 2016. Observation of ionic Coulomb blockade in nanopores. Nature Materials. en. 15. 8. 850–855. 10.1038/nmat4607. 27019385. 2016NatMa..15..850F. 1476-1122.
  15. Comtet. Jean. Grosjean. Benoit. Glushkov. Evgenii. Avsar. Ahmet. Watanabe. Kenji. Taniguchi. Takashi. Vuilleumier. Rodolphe. Bocquet. Marie-Laure. Radenovic. Aleksandra. 25 May 2020. Direct observation of water-mediated single-proton transport between hBN surface defects. Nature Nanotechnology. en. 15. 7. 598–604. 10.1038/s41565-020-0695-4. 32451503. 1906.09019. 2020NatNa..15..598C. 195316901. 1748-3387.
  16. Web site: StackPath. 2020-09-23. www.laserfocusworld.com.

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