Alec Stokes Explained

Alec Stokes
Birth Date:27 June 1919
Birth Name:Alexander Rawson Stokes
Birth Place:Macclesfield, England
Nationality:British
Fields:Physics, biophysics
Workplaces:Royal Holloway College, London
King's College London
Alma Mater:University of Cambridge
Thesis Title:Imperfect Crystals
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Thesis Year:1944
Doctoral Advisor:Lawrence Bragg
Academic Advisors:John Randall
Known For:Molecular structure of DNA
Spouse:Margaret Stokes
Children:2 sons and 1 daughter

Alexander Rawson Stokes (27 June 1919 – 6 February 2003) was a British physicist at Royal Holloway College, London and later at King's College London.[1] He was most recognised as a co-author of the second[2] of the three papers published sequentially in Nature on 25 April 1953[3] describing the correct molecular structure of DNA. The first was authored by Francis Crick and James Watson,[4] and the third by Rosalind Franklin and Raymond Gosling.

In 1993, on the 40th anniversary of the publication of the molecular structure of DNA, a plaque was erected in the Quad (courtyard) of the Strand campus of King's College London, commemorating the contributions of Franklin, Gosling, Stokes, Wilson, and Wilkins to "DNA X-ray diffraction studies".

Early life and education

Known by the name Alec,[5] [6] [7] Stokes was born in Macclesfield, Cheshire. He studied at Cheadle Hulme School in Manchester. He received a first-class degree in the natural science tripos in 1940 at Trinity College, Cambridge and then researched X-ray crystallography of Imperfect Crystals for his PhD in 1943 under the supervision of Lawrence Bragg at the Cavendish Laboratory.[8] [9]

Scientific work

Stokes lectured in physics at Royal Holloway College, London before joining John Randall's Biophysics Research Unit at King's College London in 1947. He has been credited[8] [10] as being the first person to demonstrate that the DNA molecule was probably helical in shape. Maurice Wilkins wrote in his autobiography[11] that he asked Stokes to predict what a helical structure would look like as an x-ray diffraction photograph, and that he was able to determine this by the next day through mathematical calculations made during a short train journey. Stokes continued to work on optical diffraction in large biological molecules. His publications include the books The Theory of the Optical Properties of Inhomogeneous Materials. London: E. and F.N. Spon Ltd, (1963) and The Principles of Atomic and Nuclear Physics C.J. Smith and A.R. Stokes, London, Edward Arnold, (1972) .[12]

Later life

Stokes retired from King's College London as a senior lecturer in 1982. He was a choral singer, played the piano and was an elder in his local free church, in Welwyn Garden City.[13] He died on 5 February 2003, survived by his wife, Margaret, two sons, Gordon Stokes and Ian Stokes and a daughter, Jean Stokes.

Further reading

External links

Notes and References

  1. Web site: A photo that changed the world. 2020-11-08. www.kcl.ac.uk.
  2. Wilkins. M. H. F.. Stokes. A. R.. Wilson. H. R.. Molecular structure of nucleic acids: molecular structure of deoxypentose nucleic acids. Nature. 1953. 171. 4356. 738–740. 10.1038/171738a0. 13054693. 1953Natur.171..738W . 4280080.
  3. Web site: Double Helix: 50 years of DNA. Nature. Nature Publishing Group. https://web.archive.org/web/20150522235410/http://www.nature.com/nature/dna50/archive.html. 2015-05-22.
  4. Watson. J. D.. Crick. F. H. C.. Molecular structure of nucleic acids: a structure for deoxyribose nucleic acid. Nature. 1953. 171. 4356. 737–738. 10.1038/171737a0. 13054692. 1953Natur.171..737W . 4253007.
  5. Web site: Papers of M H F Wilkins: notes by Raymond Gosling and Alec Stokes. 2020-11-08. Wellcome Library.
  6. News: Wright. Pearce. 2003-02-15. Obituary: Alexander Stokes. 2020-11-08. The Guardian.
  7. News: 5 March 2003. Alec Stokes. The Sunday Times. 2020-11-08.
  8. News: Alexander Stokes . 5 August 2014. The Telegraph. 28 February 2003.
  9. Web site: Robert. Walgate. Modest, neglected DNA pioneer dies. The Scientist. 13 March 2003. 5 August 2014.
  10. U.S. National Library of Medicine. Francis. Crick. James D. Watson. 31 March 1966. Notes concerning Watson's book, "The Double Helix". 6. https://profiles.nlm.nih.gov/spotlight/sc/catalog/nlm:nlmuid-101584582X157-doc. 2019-11-03.
  11. Book: Wilkins, Maurice. 160. The Third Man of the Double Helix: The Autobiography of Maurice Wilkins. limited. Oxford University Press. 2003. 0-19-860665-6.
  12. Wilson, Herbert R.. Herbert Wilson. Obituary: Alexander Rawson Stokes. Physics Today. January 2004. 57. 1. 67–68. 10.1063/1.1650080. 2004PhT....57a..67W . free.
  13. News: Pearce. Wright. 15 Feb 2003. Alexander Stokes. The Guardian.