Alan Garen Explained

Alan Garen
Birth Date:March 26, 1926
Birth Place:United States
Death Place:New Haven, Connecticut, U.S.
Field:Genetics
Work Institution:Yale University
Education:University of Colorado
Doctoral Advisor:Theodore T. Puck
Known For:Discovery of stop codons

Alan Garen was an American geneticist who co-discovered suppressor mutations for tRNA. The Garen lab also showed that certain triplet codons (5'-UAG, 5'-UAA, and 5'-UGA) failed to bind amino acids.[1] Thus, the Garen lab and Brenner labs are both credited with discovery of the stop codons of the genetic code.[2]

Garen was a professor at Yale University between 1963 and 2021.[3] He was a member of the National Academy of Sciences and the American Academy of Arts and Sciences.

External links

Notes and References

  1. Weigert M, Galluci E, Lanka E, Garen A . Characteristics of the genetic code in vivo . Cold Spring Harb Symp Quant Biol . 31 . 145–150 . 1966 . 4866371 . 10.1101/sqb.1966.031.01.022.
  2. Stretton AO, Kaplan S, Brenner S . Nonsense codons . Cold Spring Harb Symp Quant Biol . 31 . 173–179 . 1966 . 5237189 . 10.1101/sqb.1966.031.01.025.
  3. Web site: MB&B bids farewell to Tom Pollard and Alan Garen | Molecular Biophysics and Biochemistry.