Alan Grossman Explained

Alan D. Grossman
Workplaces:Massachusetts Institute of Technology
Awards:Eli Lilly and Company-Elanco Research Award (1997)

Alan D. Grossman, is an American microbiologist; he is currently the Praecis Professor of Biology and served head of the Department of Biology at the Massachusetts Institute of Technology from 2014-2022. He is a member of the National Academy of Sciences and the American Academy of Arts & Sciences.[1] [2]

Education

Grossman received a Bachelor of Arts in biochemistry from Brown University in 1979. He earned his Ph.D. at the University of Wisconsin–Madison in 1984.[3] Grossman completed a postdoctoral fellowship in the Department of Cellular and Developmental Biology at Harvard University before joining MIT's biology department in 1988.[4]

Career

Initially, his research was focused on characterization of bacterial chromosome segregation. His group was among the first that identified the Spo0J protein, the homologue of ParB, responsible for the process of chromosome segregation in B. subtilis.[5] He later moved on to show that Spo0J binds to specific cis-sites on the DNA in order to implement its function and identified the sequences of those cis-sites which was termed ParS.[6]

In 2006, Grossman received a life-saving heart transplant. He has discussed the experience publicly and encouraged others to consider organ donation.[7]

Notes and References

  1. Web site: Alan D. Grossman. 2022-02-05. www.nasonline.org.
  2. Web site: Alan D. Grossman. 2022-02-05. American Academy of Arts & Sciences. en.
  3. Web site: Alan D. Grossman. 2022-02-05. MIT Department of Biology. en-US.
  4. Web site: Alan D. Grossman named head of the Department of Biology. 2022-02-05. MIT News Massachusetts Institute of Technology. 4 August 2014 . en.
  5. Ireton K, Gunther NW, Grossman AD. spo0J is required for normal chromosome segregation as well as the initiation of sporulation in Bacillus subtilis. . J Bacteriol . 1994 . 176 . 17 . 5320–9 . 8071208 . 10.1128/jb.176.17.5320-5329.1994 . 196717 .
  6. Lin DC, Grossman AD. Identification and characterization of a bacterial chromosome partitioning site. . Cell . 1998 . 92 . 5 . 675–85 . 9506522 . 10.1016/s0092-8674(00)81135-6 . 1721.1/83851 . 11402267 . free .
  7. Web site: Alan Grossman shares lessons learned from his lifesaving gift. 2022-02-05. MIT School of Science. en-US.