| State: | AL |
| Type: | AL |
| Route: | 121 |
| Map Custom: | yes |
| Length Mi: | 0.854 |
| Length Ref: | [1] |
| Established: | 1970s |
| Decommissioned: | 2005 |
| Direction A: | South |
| Terminus A: | in Camp Hill |
| Direction B: | North |
| Terminus B: | in Camp Hill |
| Previous Type: | AL |
| Previous Route: | 120 |
| Next Type: | AL |
| Next Route: | 122 |
State Route 121 (SR 121) was a 0.9adj=midNaNadj=mid state highway entirely in Tallapoosa County in the east-central part of the U.S. state of Alabama. The southern terminus of the highway was at U.S. Route 280 (US 280) in Camp Hill. The northern terminus of the route was at its intersection with SR 50, also in Camp Hill.
State Route 121 began at US 280 (now old US 280) in Camp Hill, heading towards downtown Camp Hill. At downtown Camp Hill there was the town's police station, library, the old post office, and some abandoned buildings. SR 121 then ended at SR 50 in Camp Hill.
SR 121 was established in the 1970s and decommissioned three decades later in September 2005 because of the US 280 Bypass opening.