| Official Name: | Al-Masrab |
| Native Name: | المسرب |
| Pushpin Map: | Syria |
| Pushpin Mapsize: | 250 |
| Subdivision Type: | Country |
| Subdivision Type1: | Governorate |
| Subdivision Name1: | Deir ez-Zor |
| Subdivision Type2: | District |
| Subdivision Name2: | Deir ez-Zor |
| Subdivision Type3: | Subdistrict |
| Subdivision Name3: | al-Tabni |
| Settlement Type: | Village |
| Unit Pref: | Metric |
| Population As Of: | 2004 census |
| Population Total: | 4,833 |
| Timezone: | EET |
| Utc Offset: | +2 |
| Timezone Dst: | EEST |
| Utc Offset Dst: | +3 |
| Coordinates: | 35.5411°N 39.8661°W |
Al-Masrab (Arabic: المسرب, also spelled al-Musareb or el-Mesereb) is a village in eastern Syria, administratively part of the Deir ez-Zor Governorate, located along the Euphrates River, northwest of Deir ez-Zor. Nearby localities include al-Tabni to the northwest, al-Harmushiyah to the north, al-Kasrah to the northeast, al-Saawah to the east and al-Shumaytiyah to the southeast. According to the Syria Central Bureau of Statistics, al-Masrab had a population of 4,833 in the 2004 census.[1]