| Al-Khafsah Subdistrict | |
| Native Name: | ناحية الخفسة |
| Native Name Lang: | ar |
| Type: | Subdistrict |
| Mapsize: | 250x250px |
| Map Alt: | Al-Khafsah Subdistrict in Syria |
| Coor Pinpoint: | Al-Khafsah |
| Pushpin Map: | Syria |
| Pushpin Label Position: | bottom |
| Pushpin Map Caption: | Location in Syria |
| Pushpin Mapsize: | 250 |
| Subdivision Type: | Country |
| Subdivision Type1: | Governorate |
| Subdivision Name1: | Aleppo |
| Subdivision Type2: | District |
| Parts Type: | Subdistricts |
| Parts Style: | para |
| Established Title: | Established |
| Seat Type: | Seat |
| Seat: | Al-Khafsah |
| Elevation Point: | Al-Khafsah |
| Population: | 92,368 |
| Population Density Km2: | auto |
| Population As Of: | 2004 |
| Population Footnotes: | [1] |
| Area Code Type: | Area code |
| Geocode: | SY020502 |
Al-Khafsah Subdistrict (Arabic: ناحية الخفسة) is a subdistrict of Manbij District in Aleppo Governorate of northern Syria. The administrative centre is the town of Al-Khafsah.
At the 2004 census, the subdistrict had a population of 92,368.