| Ajuruxi River | |
| Pushpin Map: | Brazil |
| River System: | Amazon River |
| Mouth Coordinates: | -0.5373°N -51.5362°W |
| Subdivision Type1: | Country |
| Subdivision Name1: | Brazil |
The Ajuruxi River (pt|Rio Ajuruxi) is a river in the state of Amapá, Brazil. It is a left tributary of the lower Amazon River.
The Ajuruxi River defines the northeastern boundary of the Rio Cajari Extractive Reserve, created in 1990.