Ajit Johnson Explained

Ajit Johnson
Birth Place:Chennai, India
Workplaces:Harvard University, Dana–Farber Cancer Institute
Alma Mater:
  • University College London

Ajit Johnson Nirmal is a cancer geneticist. He has also campaigned to raise awareness on tech addiction and net neutrality.[1] [2]

Education

Born in Vellore, Johnson graduated with a bachelor's degree in biotechnology at Karunya University. Johnson graduated from University College London in 2011 and worked at the Indian Institute of Science. He earned a Doctor of Philosophy in cancer genetics and genomics from the University of Edinburgh[3] and performed his post-doctoral work at Harvard Medical School and Dana Farber Cancer Institute.[4]

Career

Research

Johnson and colleagues developed a cell based gene therapy for haemophilia patients at the National Cancer Centre Singapore.[5] [6] Johnson developed ImSig, a network-based computational framework that facilitates the characterization of immune cells within the tumor microenvironment.[7] Johnson's work involves multi-dimensional characterization (genetic, transcriptional, spatial and biophysical attributes) of the tumor ecosystem [8] and understanding the differences in molecular signature of immune cells [9] across tumours.

External links

Notes and References

  1. News: These Posters Perfectly Sum Up Twentysomethings' Addiction to the Internet. Cashin. Declan. BuzzFeed.
  2. News: The Truth About #ThisGeneration. Bulkley. McKenna. www.huffingtonpost.com.
  3. Web site: British Library Thesis Collection. Nirmal. Ajit Johnson. 2018-09-28. University of Edinburgh.
  4. Web site: Nirmal . Ajit Johnson . Harvard Scholar- Ajit Johnson Nirmal .
  5. Sivalingam. Jaichandran. Kenanov. Dimitar. Han. Hao. Nirmal. Ajit Johnson. Ng. Wai Har. Lee. Sze Sing. Masilamani. Jeyakumar. Phan. Toan Thang. Maurer-Stroh. Sebastian. Kon. Oi Lian. 2016-03-01. Multidimensional Genome-wide Analyses Show Accurate FVIII Integration by ZFN in Primary Human Cells. Molecular Therapy. 24. 3. 607–619. 10.1038/mt.2015.223. 1525-0016. 4786920. 26689265.
  6. Lee. Sze Sing. Sivalingam. Jaichandran. Nirmal. Ajit J.. Ng. Wai Har. Kee. Irene. Song. In Chin. Kiong. Chin Yong. Gales. Kristoffer A.. Chua. Frederic. Pena. Edgar M.. Ogden. Bryan E.. 2018-07-01. Durable engraftment of genetically modified FVIII‐secreting autologous bone marrow stromal cells in the intramedullary microenvironment. Journal of Cellular and Molecular Medicine. 22. 7. 3698–3702. 10.1111/jcmm.13648. 1582-1838. 6010829. 29682884.
  7. Nirmal. Ajit J.. Regan. Tim. Shih. Barbara B.. Hume. David A.. Sims. Andrew H.. Freeman. Tom C.. 2018-09-28. Immune Cell Gene Signatures for Profiling the Microenvironment of Solid Tumors. Cancer Immunology Research. en. 6. 11. 1388–1400. 10.1158/2326-6066.CIR-18-0342. 2326-6066. 30266715. free. 20.500.11820/e72749a6-a382-44ef-8f93-d58b3353e97c. free.
  8. Web site: Harvard Scholar Page. Nirmal. Ajit Johnson. Harvard University.
  9. Shih. Barbara B. Nirmal. Ajit J. Headon. Denis J. Akbar. Arne N. Mabbott. Neil A. Freeman. Tom C. 2017-04-01. Derivation of marker gene signatures from human skin and their use in the interpretation of the transcriptional changes associated with dermatological disorders. The Journal of Pathology. 241. 5. 600–613. 10.1002/path.4864. 0022-3417. 5363360. 28008606.

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