| Aguapeí River | |
| Pushpin Map: | Brazil |
| River System: | Jauru River |
| Source1 Location: | Mato Grosso state |
| Mouth Coordinates: | -15.8731°N -58.3986°W |
| Subdivision Type1: | Country |
| Subdivision Name1: | Brazil |
The Aguapeí River (Portuguese: Rio Aguapeí) is a river of Mato Grosso state in western Brazil.It is a tributary of the Jauru River, which in turn is a tributary of the Paraguay River.
The Aguapeí River rises in the Serra de Santa Bárbara State Park, then runs in a roughly northeast direction until it meets the Jauru.