| Agona District | |
| Settlement Type: | Former District |
| Pushpin Map: | Ghana |
| Pushpin Map Caption: | Location of Agona District within Central |
| Subdivision Type: | Country |
| Subdivision Name: |  Ghana |
| Subdivision Type1: | Region |
| Subdivision Name1: | Central |
| Subdivision Type2: | Capital |
| Subdivision Name2: | Agona Swedru |
| Leader Title: | District Executive |
| Area Total Km2: | 632 |
| Population Blank1 Title: | Ethnicity |
| Population Blank1: | Akan people |
| Timezone: | GMT |
| Utc Offset: | +0 |
| Coordinates: | 5.5327°N -0.7033°W |
| Iso Code: | GH-CP-AG |
Agona District is a former district that was located in Central Region, Ghana. Originally created as an ordinary district assembly in 1988. However on 29 February 2008, it was split off into two new districts: Agona West District (which was elevated to municipal district assembly status on that same year; capital: Agona Swedru) and Agona East District (capital: Nsaba). The district assembly was located in the northeast part of Central Region and had Agona Swedru as its capital town.