Aganodine Explained

Aganodine is a guanidine that activates presynaptic imidazoline receptors.[1] Through its agonism at imidazoline receptors, aganodine inhibits the presynaptic release of norepinephrine.[2]

Notes and References

  1. 9298527. 1997. Molderings. GJ. Likungu. J. Jakschik. J. Göthert. M. Presynaptic imidazoline receptors and non-adrenoceptor 3H-idazoxan binding sites in human cardiovascular tissues. 122. 1. 43–50. 10.1038/sj.bjp.0701343. 1564902. British Journal of Pharmacology.
  2. Göthert. M.. Brüss. M.. Bönisch. H.. Molderings. G.J.. Presynaptic Imidazoline Receptors. Annals of the New York Academy of Sciences. 1999. 881. 171–184. 10.1111/j.1749-6632.1999.tb09356.x. 10415912. 12242403.

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