| Tourney Name: | African Cup of Champions Clubs |
| Year: | 1980 |
| Num Teams: | 31 |
| Confederations: | 1 |
| Champion Other: |  Canon Yaoundé |
| Count: | 3 |
| Second Other: | AS Bilima |
| Matches: | 56 |
| Goals: | 155 |
| Top Scorer: | Jean Manga-Onguéné (9 goals) |
| Player: | Jean Manga-Onguéné |
| Prevseason: | 1979 |
| Nextseason: | 1981 |
The 1980 African Cup of Champions Clubs was the 16th edition of the annual international club football competition held in the CAF region (Africa), the African Cup of Champions Clubs. It determined that year's club champion of association football in Africa.
The tournament was played by 31 teams and was used a playoff scheme with home and away matches. Canon Yaoundé from Cameroon won that final, and became for the third time CAF club champion.
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| African Cup of Champions Clubs 1980 Canon Yaoundé Third title |
The top scorers from the 1980 African Cup of Champions Clubs are as follows:
| Rank | Name | Team | Goals |
|---|---|---|---|
| 1 | Jean Manga Onguéné | Canon Yaoundé | 9 |
| 2 | Ayel Mayélé | AS Bilima | 5 |
| 3 | Lakhdar Belloumi | MP Alger | 4 |
| Ibrahim Alikali | Bendel Insurance | 4 | |
| 5 | Théophile Abega | Canon Yaoundé | 3 |
 Andrew Obunga | Gor Mahia | 3 | |
| 7 | Abdelwahab Zenir | MP Alger | 2 |
| Grégoire M'Bida | Canon Yaoundé | 2 | |
 ... Tchibundo | Anges ABC | 2 | |
 Dan Kayede | Hearts of Oak | 2 | |
 Léon Gbizié | Stella Club d'Adjamé | 2 | |
| Francis Doé | Stella Club d'Adjamé | 2 | |
| Jean Mandiangu | AS Bilima | 2 |