| Kwahu North (Afram Plains) District | |
| Settlement Type: | Former District |
| Pushpin Map: | Ghana |
| Pushpin Map Caption: | Location of Kwahu North (Afram Plains) District within Eastern |
| Subdivision Type: | Country |
| Subdivision Name: |  Ghana |
| Subdivision Type1: | Region |
| Subdivision Type2: | Capital |
| Subdivision Name2: | Donkorkrom |
| Leader Title: | District Executive |
| Leader Name: | Samuel Kena |
| Area Total Km2: | 3559 |
| Population As Of: | 2013 |
| Population Total: | — |
| Timezone: | GMT |
| Utc Offset: | +0 |
| Coordinates: | 7.0519°N -0.08°W |
| Iso Code: | GH-EP-AP |
Afram Plains District is a former district that was located in Eastern Region, Ghana. Originally created as an ordinary district assembly in 1988 when it was known as Kwahu North District, which was created from the former Kwahu District Council, until it was later renamed to become Afram Plains District in 1993. However on 19 June 2012, it was split off into two new districts: Kwahu Afram Plains North District (capital: Donkorkrom) and Kwahu Afram Plains South District (capital: Tease). The district assembly was located in the northern part of Eastern Region and had Donkorkrom as its capital town.
In Kwahu Afram Plains North District, they currently have Betty Mensah, who succeeded Emmanuel Aboagye Didie as the member of Parliament and Samuel Kena as the district chief executive. Samuel Kena is a retired educationist.
Area well noted for fresh water fishing and production of smoked fish. Most major markets in Ghana receive their smoked fish from this area. Traditionally, owned by the Kwahu but occupied much by the Ewes and Krobos due to the fishing.