| Afame | |
| Settlement Type: | Village |
| Pushpin Map: | Guam |
| Pushpin Label Position: | left |
| Pushpin Mapsize: | 300 |
| Subdivision Type: | Country |
| Subdivision Name: |  United States |
| Subdivision Type1: | Territory |
| Subdivision Name1: |  Guam |
| Unit Pref: | Imperial |
| Coordinates: | 13.4558°N 144.7586°W |
Afame, also Afami, is a census-designated place in central Guam.[1] It is located in the village of Sinajana, just south of Hagåtña.