| Aeropesca Colombia Flight 221 | |
| Occurrence Type: | Accident |
| Date: | 26 August 1981 |
| Summary: | Controlled flight into terrain (CFIT) |
| Site: | Cerro Matiqui, Colombia |
| Aircraft Type: | Vickers Viscount 745D |
| Aircraft Name: | Ciudad de Popayana |
| Operator: | Aeropesca Colombia |
| Tail Number: | HK-1320 |
| Origin: | Florencia-Gustavo Artunduaga Paredes Airport (FLA/SKFL), Florencia, Colombia |
| Destination: | Neiva Airport, Colombia |
| Passengers: | 44 |
| Crew: | 6 |
| Fatalities: | 50 |
| Survivors: | 0 |
Aeropesca Colombia Flight 221 was an internal scheduled passenger flight from Florencia Airport to Neiva Airport in Colombia. On 26 August 1981 it was being operated by a Vickers Viscount turboprop airliner registered in Colombia as HK-1320 when it collided with Mount Santa Elana, an Andean mountain peak, destroying the aircraft and killing all 50 on board.
The investigation by the Colombian authorities concluded the probable cause was "continuing VFR in meteorological conditions below the minimum laid down in the Manual of Colombian air routes".
The aircraft was a four-engined Vickers Viscount 745D turboprop airliner registered HK-1320 with Vickers construction number 112, it first flew on 22 February 1956 in the United Kingdom and was delivered to Capital Airlines in the United States on 3 March 1956. After service with Capital, Austrian Airlines and Aloha Airlines it was bought by Aeropesca Colombia in 1971.